Aneurysm Occlusion Ribbon with Distal-Proximal Loop Variation
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Solution Overview
Problem
Current methods for treating cerebral aneurysms are inadequate, as they often fail to effectively occlude the aneurysm sac and secure the neck, leading to potential rupture and hemorrhage, with existing devices either dispersing within the aneurysm or failing to conform to its contours.
Innovation Solution
An intrasaccular aneurysm occlusion device featuring a longitudinal mesh ribbon with distal-to-proximal series of loops or segments that accumulate and overlap to form an arcuate three-dimensional occlusive mass, allowing for variation in size, shape, and orientation to densely occlude the sac and conform to its contours.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If existing occlusion devices are used, then the aneurysm treatment can be performed, but the devices fail to effectively occlude the aneurysm sac and secure the neck, leading to potential rupture
Solution Approach 1:
The occlusion device is divided into multiple loops or segments arranged in a distal-to-proximal series along the longitudinal mesh ribbon. Each loop can be independently sized and shaped to match specific contours of the aneurysm sac, allowing the device to adapt to varying anatomical geometries while maintaining reliable occlusion of the sac and neck region
Solution Approach 2:
The loops or segments exhibit distal-to-proximal variation in size, shape, and orientation, with each segment having locally optimized properties. Distal loops may be larger to fill the sac body, while proximal loops are smaller and more densely packed to secure the neck, creating a gradient structure that addresses different functional requirements at different locations
2Reliability
If existing devices disperse within the aneurysm, then deployment is simple, but complete occlusion and neck coverage cannot be achieved
Solution Approach 1:
The loops or segments are configured to form an arcuate three-dimensional occlusive mass that conforms to the curved contours of the aneurysm sac. The arcuate arrangement of loops creates a spherical or semi-spherical packing structure that naturally fills the sac volume while the varying orientations of loops ensure complete coverage of the neck region
Solution Approach 2:
The longitudinal mesh ribbon accumulates and overlaps onto itself in a nested fashion, with distal loops forming the outer layer and proximal loops nesting within to create a dense packed structure. This nested arrangement allows the device to maintain its occlusive function while simplifying deployment through catheter delivery
3Adaptability or versatility
If uniform loops are used in the mesh ribbon, then manufacturing is simplified, but the device cannot conform to the varying contours of the aneurysm sac
Solution Approach 1:
The mesh ribbon incorporates distal-to-proximal variation in loop size, shape, and orientation, with each segment having locally optimized properties. This gradient structure allows the device to adapt to varying anatomical geometries of different aneurysms, with larger distal loops filling the sac body and smaller proximal loops securing the neck
Solution Approach 2:
The loop parameters (size, shape, orientation) are systematically varied along the longitudinal axis of the mesh ribbon, creating a gradient structure. This parameter variation allows the device to conform to the three-dimensional contours of the aneurysm sac while maintaining a regular, manufacturable pattern that can be produced using controlled deformation techniques
Data Source
AI summary
This invention is an intrasacular aneurysm occlusion device with a longitudinal mesh ribbon having a series of loops or segments with distal-to-proximal variation in their sizes, shapes, or orientations. For example, loops or segments can be progressively smaller in size and/or progressively more curved as one views the series in a distal-to-proximal direction. The device may also enable a user to selectively and remotely bend, steer, or elongate the loops or segments in real time as the ribbon is being deployed into an aneurysm sac.