Angiography-OCT Synchronization Using Premeasured Pullback Delay
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Solution Overview
Problem
Existing imaging systems face challenges in synchronizing multiple imaging modalities, such as OCT and angiography, due to computational intensity and anatomical dependencies, leading to inaccurate delay measurements and confusion in image interpretation during vascular procedures.
Innovation Solution
Implementing a system with a graphical user interface (GUI) and methods for calculating angio delay using controlled pullbacks, linear regression, and spinning devices with geometric windows to measure accurate delay times, independent of individual pullbacks, and storing these measurements for consistent synchronization across operating rooms.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If coregistration process is used to calculate delay on each angio frame, then synchronization accuracy is improved, but computational complexity increases and the process becomes error-prone
Solution Approach 1:
The system performs delay measurement once during a controlled pullback procedure before clinical use, storing the measured delay value for reuse. This preliminary action eliminates the need for continuous computational coregistration during actual angiography, reducing real-time computational complexity while maintaining synchronization accuracy through the pre-measured delay value.
2Measurement precision
If coregistration process is used to calculate delay, then synchronization is achieved, but the process becomes dependent on individual pullback anatomy reducing reliability
Solution Approach 1:
The system extracts the delay measurement from the variable anatomical context by using a controlled pullback with visible markers (radiopaque markers or spinning device) that provide consistent reference points regardless of anatomy. This extracted delay value is then applied universally across different pullbacks and anatomies, improving reliability and consistency.
3Ease of operation
If multiple imaging modalities are displayed side-by-side, then image interpretation is enhanced, but users may obtain incorrect impressions of temporal association
Solution Approach 1:
The system measures and determines the actual delay time between different imaging modalities (e.g., OCT and angiography) and uses this feedback information to either adjust the display timing or provide visual indicators of the temporal offset. This ensures users understand the true temporal relationships between images while still benefiting from side-by-side comparison for enhanced interpretation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Achieves precise synchronization of multiple imaging modalities, reducing computational complexity and anatomical dependencies, thereby enhancing image interpretation accuracy and consistency in vascular procedures.
Implementation Method 1
The rotating portion operates to rotate around an axis over, or adjacent to, the stationary portion such that the rotating portion acts as a shutter where the shutter is open in a case where the windows or areas of the rotating portion and of the stationary portion are partially or completely overlapping, and where the shutter is otherwise closed
Data Source
AI summary
One or more devices, systems, methods and storage mediums for optical imaging medical devices, such as, but not limited to, Optical Coherence Tomography (OCT), single mode OCT, and/or multi-modal OCT apparatuses and systems, and methods and storage mediums for use with same, for viewing, controlling, updating, and emphasizing imaging modalities, for performing angio delay determination to find relative delay difference(s) between angio image(s) and another modality image(s), and/or for performing synchronization technique(s) are provided herein. One or more embodiments provide at least one intuitive Graphical User Interface (GUI), method, device, apparatus, system, or storage medium to comprehend information, to improve or maximize accuracy in one or more images and to perform angio delay (or delay time) determination and/or synchronization. In addition to controlling one or more imaging modalities, the GUI may operate for one or more applications, including, but not limited to, angio delay measurement(s), synchronization, co-registration, and imaging.


