Anhydrous Silver Compositions for Stable Antimicrobial Delivery
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Solution Overview
Problem
There is a need for effective and efficient delivery and use of antimicrobial agents, as existing technologies struggle to provide stable and bioavailable forms of silver with potent antimicrobial properties.
Innovation Solution
The development of anhydrous compositions that include colloidal silver particles with a silver core surrounded by a multivalent silver oxide coating, combined with a substrate, which are processed to remove water, resulting in a stable and bioavailable antimicrobial powder.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If aqueous silver compositions are used to deliver antimicrobial properties, then antimicrobial activity is provided, but stability and bioavailability are compromised due to water content
Solution Approach 1:
The patent applies phase transition by removing water from the aqueous silver composition to create an anhydrous composition. This phase change from aqueous to anhydrous state eliminates water-related instability while preserving silver particles' antimicrobial activity, directly resolving the contradiction between maintaining antimicrobial function and achieving composition stability.
Solution Approach 2:
The patent extracts water from the aqueous silver composition through drying processes, isolating the silver particles in an anhydrous form. This extraction of the problematic water component maintains silver's antimicrobial properties while eliminating water-induced instability, thereby resolving the stability-activity contradiction.
2Reliability
If conventional silver compositions are used, then antimicrobial properties are provided, but side-reactions such as discoloration and oxidation occur
Solution Approach 1:
The patent creates an inert environment by forming an anhydrous composition that excludes water and oxygen from reacting with silver particles. This inert atmosphere prevents oxidation and discoloration side-reactions while maintaining the silver particles' antimicrobial activity, resolving the contradiction between providing antimicrobial properties and avoiding harmful side-reactions.
Solution Approach 2:
The patent converts the potential harm of water (which causes instability and side-reactions) into a benefit by completely removing it to create an anhydrous state. This eliminates water-related problems while preserving the essential antimicrobial function, transforming a harmful condition into a beneficial stable form.
3Reliability
If silver particles are made bioavailable through aqueous forms, then absorption is improved, but stability is reduced due to water interaction
Solution Approach 1:
The patent uses phase transition to convert aqueous silver particles to anhydrous form, eliminating water interactions that cause instability while maintaining particle integrity and bioavailability. This phase change resolves the contradiction by creating a stable form that remains biologically active.
Solution Approach 2:
The patent creates a composite anhydrous composition where silver particles are combined with substrate materials in a water-free environment. This composite structure enhances stability while preserving silver's bioavailability and antimicrobial properties, resolving the stability-bioavailability contradiction.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The anhydrous compositions demonstrate potent antimicrobial properties, are stable and bioavailable, and can be effectively used in various applications without causing side-reactions such as discoloration or oxidation.
Implementation Method 1
a silver particle has a silver core surrounded by a multivalent silver oxide coating
Implementation Method 2
processed to remove water, resulting in a stable and bioavailable antimicrobial powder
Data Source
AI summary
Compositions that contain a substrate and silver particles are provided. where the composition are anhydrous, optionally having antimicrobial properties in either the anhydrous or a rehydrated form.