Animal Oral Solid Composition Dosing Palatability

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Solution Overview

Problem

Current methods for administering medications and nutraceuticals to animals via the oral route face challenges due to unpleasant tastes and textures, leading to low compliance and difficulty in ensuring precise dosing, especially in solid forms, which often result in incomplete treatment and economic inefficiencies.

Innovation Solution

A solid composition comprising 5-30% fatty materials, 0.001-55% active substances, and 20-95% appetizing materials, obtained by compressing a fluid granulate using a broth cube press, ensuring homogeneous weight and palatability, suitable for domestic animals like dogs, cats, and horses.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If medications are administered in solid form to animals, then dosing precision is improved, but palatability and animal acceptance deteriorate due to unpleasant taste and texture

Engineering Contradiction:
Improvedosing precisionVSAvoidanimal acceptance
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent combines medications with palatable materials (flavorings, fragrances, nutritious substances) to create a unified solid composition that is both accurately dosed and appealing to animals. The medication is integrated into a matrix containing attractants and flavor enhancers, making the entire composition desirable for consumption.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite solid material consisting of multiple components: the active medication, binders, fillers, flavorings, fragrances, and nutritious substances. This composite structure allows simultaneous achievement of dosing precision through controlled formulation and palatability through appealing sensory characteristics.

Inventive Principle:
Principle #40Composite materials

2Ease of operation

If medications are administered in solid form, then handling and administration ease is improved, but dosing uniformity and homogeneity worsen due to difficulty in ensuring consistent quantity of active substance

Engineering Contradiction:
Improvehandling easeVSAvoiddosing uniformity
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The patent achieves homogeneity by thoroughly mixing the medication with other ingredients to create a uniform solid composition. The consistent particle size distribution and intimate mixing ensure that each unit of the solid form contains the intended quantity of active substance, providing both handling ease and dosing uniformity.

Inventive Principle:
Principle #33Homogeneity

Solution Approach 2:

The solid composition can be divided into discrete units (such as tablets, capsules, or chewable pieces) that each contain a precise amount of medication. This segmentation allows for easy handling and administration while ensuring that each unit provides uniform dosing.

Inventive Principle:
Principle #1Segmentation

3Reliability

If parenteral routes of administration are used, then therapeutic action is ensured, but animal welfare and comfort deteriorate due to pain, hematomas, and requirement for restraint

Engineering Contradiction:
Improvetherapeutic actionVSAvoidanimal suffering
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent converts the potential harm of medication administration by transforming an invasive parenteral route into a non-invasive oral route. The medication is delivered through the digestive system in a palatable solid form, eliminating pain, hematomas, and the need for restraint while maintaining therapeutic effectiveness.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The solid composition acts as an intermediary vehicle that delivers the medication through the oral route. Instead of direct injection into muscle or vein, the medication is embedded in a solid form that dissolves or breaks down in the digestive system, providing therapeutic action without the harmful effects of parenteral administration.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Ease of operation

If liquid or semi-solid formulations are used for oral administration, then palatability is improved, but dosing precision and control worsen

Engineering Contradiction:
ImprovepalatabilityVSAvoiddosing control
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent changes the physical state parameter from liquid/semi-solid to solid form. This parameter change allows the composition to maintain palatability through appealing texture and flavor while enabling precise dosing control through discrete, measurable units such as tablets or capsules with defined weight and composition.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method provides a palatable and easily consumable solid form that ensures precise dosing and high acceptance by animals, overcoming the limitations of existing techniques in texture and dosing accuracy, while being economically viable for industrial production.

Implementation Method 1

obtained by compression with a broth press cubes of a fluid homogeneous granulate

Methodology Applied
Scientific EffectCompression: Compression

Data Source

PatentEP2755498B1Composition for oral administration to animals and production method
Publication Date: 2018.02.07 FRIULCHEM
  • EP2755498B1 patent drawingFigure 1
  • EP2755498B1 patent drawingFigure 2

AI summary

The present invention relates to a solid appetising composition, the use thereof and the production method of same, said composition comprising in relation to the total weight thereof: 5 to 30 wt.-%, preferably 8 to 20 wt.-%, of at least one fat, selected from a liquid oil, a fatty substance, a wax or a mixture of same, wherein the liquid oil cannot constitute more than 8 wt.-% of the composition; 0.001 to 85 wt.-% of at least one active substance; and 20 to 95 wt.-%, preferably 40 to 70 wt.-% of an appetising material, intended for use as a drug, nutraceutical or food supplement, for oral administration to mammals, not including humans, in particular for domestic animals such as dogs, cats and horses. Said solid composition is obtained by mixing the components, vaporising the fatty substances, size-grading the dry and fluid granular material, and compressing said granular material with a bouillon cube press.