Anisotropic Haptics for Predictable Accommodating IOL Base State
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Solution Overview
Problem
There is variability in capsular bag size and imperfect techniques for measuring capsular sizes, leading to unpredictable base states and accommodation responses in accommodating intraocular lenses after implantation, due to anatomical variations and post-implant changes.
Innovation Solution
An accommodating intraocular lens design featuring an optic portion with a peripheral non-optic portion that is sensitive to radial forces over anterior-to-posterior forces, allowing fluid movement between fluid chambers to change optical parameters in response to ciliary muscle movement, thereby reshaping the capsule in a predictable manner.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If accommodating intraocular lenses are implanted to provide near and distance vision, then accommodation function is improved, but variability in capsular bag size and post-implant changes lead to unpredictable base states
Solution Approach 1:
The haptic is designed with anisotropic mechanical properties, being stiffer in the anterior-to-posterior direction and more compliant in the radial direction. This parameter change in stiffness orientation allows the haptic to resist capsular forces that would otherwise unpredictably alter the lens base state, while still permitting the desired accommodation function through radial deformation.
Solution Approach 2:
The haptic exhibits different stiffness characteristics in different directions: stiffer in the anterior-to-posterior direction to maintain base state stability, and more compliant in the radial direction to allow accommodation. This local quality differentiation resolves the contradiction between maintaining predictable base state and enabling accommodation function.
2Adaptability or versatility
If the peripheral non-optic portion is made sensitive to radial forces to enable accommodation, then accommodation sensitivity is improved, but sensitivity to anterior-to-posterior forces may cause unpredictable base state changes
Solution Approach 1:
The haptic's stiffness parameter is differentiated by direction: more compliant in the radial direction to detect ciliary muscle forces for accommodation, and stiffer in the anterior-to-posterior direction to resist forces that would cause unpredictable base state changes. This anisotropic parameter design resolves the contradiction between accommodation sensitivity and base state stability.
3Stability of the object's composition
If the haptic is made stiffer to reduce post-implant changes, then stability is improved, but accommodation response may be reduced
Solution Approach 1:
The haptic exhibits direction-dependent stiffness: stiffer in the anterior-to-posterior direction to reduce post-implant changes and maintain stability, while more compliant in the radial direction to preserve accommodation response. This local quality differentiation resolves the contradiction between stability and adaptability.
Solution Approach 2:
The stiffness parameter of the haptic is anisotropically distributed, being higher in the anterior-to-posterior direction for stability and lower in the radial direction for accommodation response. This parameter differentiation allows the haptic to simultaneously achieve both stability and accommodation functionality.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The design reduces variations in the base state of the intraocular lens, maintaining optical quality and accommodation sensitivity while minimizing astigmatism and post-implant changes, ensuring consistent performance across different capsular bag sizes and healing responses.
Implementation Method 1
the peripheral non-optic portion is adapted to deform in response to forces on the peripheral non-optic portion due to ciliary muscle movement to thereby move a fluid between the peripheral fluid chamber and the optic fluid chamber
Implementation Method 2
the peripheral non-optic portion is adapted to be more sensitive to forces in the radial direction that it is to forces in the anterior-to-posterior direction
Data Source
AI summary
Accommodating intraocular lenses and methods of use. The accommodating intraocular lenses include peripheral regions that are adapted to be more responsive to certain types of forces than to other types of forces. For example, the accommodating intraocular lenses can include haptics that are stiffer in an anterior-to-posterior direction than in a radial direction.