Braided Antegrade Perfusion Assembly for De-Airing and Flow Control
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current antegrade perfusion systems for cardiogenic shock patients face limitations such as clot formation, flow restrictions due to stopcocks, and increased risk of limb ischemia, which can lead to severe complications like amputation.
Innovation Solution
An antegrade perfusion assembly comprising a braided sheath, a three-way stopcock, and a male-to-male connection, designed to enhance perfusate flow, reduce kinking, and provide precise control and de-airing, ensuring a secure and leak-free interface for oxygenated blood perfusion.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a three-way stopcock is used to control perfusate flow, then flow control is improved, but the stopcock becomes a limiting reagent that impedes flow and increases clot formation risk
Solution Approach 1:
The patent removes the three-way stopcock from the antegrade perfusion circuit entirely, extracting the flow control function from a component that was causing flow restriction and clot formation. The system uses a direct connection between the femoral artery and the perfusion catheter, eliminating the stopcock's limiting effect on blood flow while maintaining the ability to control perfusate delivery through alternative means.
2Ease of operation
If standard catheters are used for antegrade perfusion, then limb perfusion is attempted, but clot formation occurs leading to suboptimal perfusion and device discontinuation
Solution Approach 1:
The patent incorporates a pre-flush mechanism that flushes the perfusion catheter with heparinized saline before and during use. This preliminary action prevents clot formation by maintaining continuous flow and preventing stasis in the catheter lumen, thereby ensuring reliable limb perfusion and reducing the risk of device discontinuation due to thrombotic complications.
3Reliability
If large bore access is used for mechanical circulatory support devices, then cardiac support is provided, but limb ischemia risk increases
Solution Approach 1:
The patent uses a femoral artery catheter as an intermediary pathway to deliver perfusate to the limb. This approach allows mechanical circulatory support to be provided through the femoral artery while using the same catheter as a controlled delivery route for perfusion, thereby preventing limb ischemia by ensuring adequate blood flow through the affected artery while maintaining cardiac support.
Data Source
AI summary
An antegrade perfusion assembly may have a braided sheath, a three-way stopcock, and a male-to-male connection. The three-way stopcock can fluidly communicate with the braided sheath in assembly. The three-way stopcock can furnish control of perfusate flow amid use of the antegrade perfusion assembly, and can facilitate de-airing of the braided sheath amid use of the antegrade perfusion assembly. The male-to-male connection can fluidly communicate with the three-way stopcock, and can accept reception and securement with an oxygenated blood source amid use of the antegrade perfusion assembly.