Anthranilic Diamide Cyclodextrin Inclusion Complexes for Propagule Coating
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Anthranilic diamides have low water solubility, making it difficult to achieve insecticidally effective concentrations in geotropic propagules and developing roots, and their absorption is hindered by the growing medium, requiring higher doses and leading to vulnerability until absorbed.
Innovation Solution
A composition comprising anthranilic diamides and cyclodextrins, with a weight ratio of 1:10 to 10:1, is used to improve water solubility and absorption, forming inclusion complexes that are applied as a coating to geotropic propagules, enhancing protection against phytophagous insect pests.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If anthranilic diamide insecticides are applied to propagules, then insecticidal protection is provided, but low water solubility impedes absorption and mobilization into propagules and developing roots
Solution Approach 1:
The patent uses cyclodextrins as intermediary substances to solubilize anthranilic diamide insecticides. The cyclodextrin molecules form inclusion complexes with the hydrophobic insecticide molecules, creating water-soluble complexes that can be readily absorbed by propagules and transported to developing roots, thereby resolving the solubility-absorption contradiction
Solution Approach 2:
The patent changes the physical-chemical parameters of the anthranilic diamide insecticide by forming inclusion complexes with cyclodextrins. This transformation converts the hydrophobic, water-insoluble insecticide into a water-soluble complex form, enabling effective absorption and mobilization while maintaining insecticidal activity
2Reliability
If greater amounts of anthranilic diamides are applied to achieve effective concentrations in foliage, then protection of expanding foliage is improved, but the cost and environmental load increase
Solution Approach 1:
Cyclodextrins act as mediators that enhance the bioavailability and transport efficiency of anthranilic diamides. By forming soluble complexes, they enable the insecticide to be more effectively taken up by propagules and transported to expanding foliage, achieving adequate protection with lower application rates
Solution Approach 2:
The inclusion complexes provide continuous availability of the insecticide for absorption and transport throughout the plant's growth. The cyclodextrin carrier maintains solubility and facilitates ongoing mobilization of the insecticide to developing tissues, ensuring sustained protection without requiring repeated high-dose applications
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition significantly increases the absorption of anthranilic diamides into propagules and developing roots, providing effective insecticidal protection to both lower and upper foliage, even beyond the initial growing season, effectively controlling phytophagous insect pests.
Implementation Method 1
compositions comprising anthranilic diamides and cyclodextrins... the ratio of component (b) to component (a) is about 1:10 to about 10:1 by weight
Data Source
AI summary
Disclosed is an insecticidal composition comprising by weight based on the total weight of the composition:a) from about 9 to about 91% of one or more anthranilic diamide insecticides; and(b) from about 9 to about 91% of a cyclodextrin;wherein the ratio of component (b) to component (a) is about 1:10 to about 10:1 by weight.Also disclosed are inclusion complexes of the anthranilic diamide insecticides with the cyclodextrin.Also disclosed is a geotropic propagule coated with an insecticidally effective amount of the aforedescribed composition. Further disclosed is a liquid composition comprising the insecticidal composition, and a method for protecting a geotropic propagule and plant derived therefrom from a phytophagous insect pest.