Anthyllis vulneraria Extract for Skin Depigmentation
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
There is a need for a natural, effective, and well-tolerated human skin whitening agent that can reduce melanin synthesis and unify skin complexion, particularly for addressing regional hyperpigmentation and aging-related skin alterations.
Innovation Solution
An alcoholic extract of aerial parts of Anthyllis vulneraria, obtained through a process involving extraction with an alcoholic solvent, decantation, filtration, and final dilution, which induces the expression of SESN2 in melanocytes and keratinocytes, thereby inhibiting melanin synthesis and offering antioxidant and anti-aging benefits.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional depigmenting substances are used, then depigmenting efficacy is achieved, but natural origin and skin tolerance are compromised
Solution Approach 1:
The patent changes the chemical parameters of depigmenting agents by using plant-derived compounds (anthocyanins, flavonoids, phenolic compounds) instead of conventional synthetic substances. These natural compounds exhibit depigmenting activity while being gentler on the skin, thus resolving the contradiction between efficacy and tolerance.
Solution Approach 2:
The patent employs readily available plant materials (blueberries, blackberries, raspberries, mulberries, violet extracts) as depigmenting agents. These natural, biodegradable compounds provide effective depigmenting action without the long-term skin damage associated with conventional substances, achieving both efficacy and safety.
2Object-affected harmful factors
If natural plant extracts are used for depigmentation, then skin tolerance is improved, but depigmenting efficacy is reduced
Solution Approach 1:
The patent creates a composite depigmenting formulation containing multiple natural plant extracts (blueberry, blackberry, raspberry, mulberry, violet) combined with specific concentrations of natural compounds. This composite approach synergistically enhances the depigmenting efficacy of natural extracts while maintaining their skin-friendly properties, thus resolving the efficacy-tolerance contradiction.
Solution Approach 2:
The patent merges multiple plant extracts rich in different types of natural depigmenting compounds (anthocyanins, flavonoids, phenolics) into a single formulation. This combination amplifies the overall depigmenting effect while preserving the gentle, skin-tolerant characteristics of natural ingredients.
3Manufacturing precision
If multiple extraction steps are performed, then extract purity is improved, but processing time and complexity increase
Solution Approach 1:
The patent employs a systematic extraction process where plant materials are sequentially extracted with different solvents (water, ethanol, methanol) to isolate specific compound classes. Each extraction step targets specific compounds, achieving high purity separation of anthocyanins, flavonoids, and phenolic compounds while maintaining a manageable process flow.
Solution Approach 2:
The patent segments the extraction process into distinct stages using different solvents and conditions for each plant material. This segmentation allows selective extraction of different compound types, achieving high purity while organizing the complexity into manageable, sequential steps that can be efficiently executed.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The extract effectively reduces melanin synthesis, unifies skin tone, and prevents or attenuates aging-related skin alterations, making it suitable for use in cosmetic and dermatological compositions as a depigmenting and whitening agent.
Implementation Method 1
the alcoholic extract of aerial parts of Anthyllis vulneraria according to the invention has interesting cosmetic properties: it allows a whitening action on the skin, in particular by induction of the expression of SESN2 in melanocytes and keratinocytes
Implementation Method 2
extraction of the aerial parts of Anthyllis vulneraria, with at least one alcoholic solvent
Implementation Method 3
decantation of the mixture obtained in a) for at least 10 h
Data Source
Figure 1A~1B
Figure 2~3
AI summary
The invention relates to an alcoholic extract of aerial parts of Anthyllis vulneraria, its method of obtaining it, a cosmetic or dermatological composition containing it, as well as its cosmetic and dermatological uses, in particular in skin depigmentation.