Anti-Inflammatory Extract Mixture With Low Drug Interaction Risk
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Solution Overview
Problem
Current pharmacological treatments for allergic and inflammatory conditions, such as antihistamines and corticosteroids, often have significant side effects, including chemical and hormonal impacts, limiting their long-term use and potential for drug interactions.
Innovation Solution
A novel mixture comprising boswellia, blackcurrant, helichrysum, perilla, and quercetin, optionally with feverfew, elderberry, or probiotic bacteria, which interferes with Th2-type allergic inflammation and autoimmune responses without interfering with cytochrome P450 activity, allowing for safe and effective combination or complementary therapy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If antihistamines and corticosteroids are used to treat allergic and inflammatory conditions, then therapeutic effectiveness is improved, but side effects and drug interactions increase
Solution Approach 1:
The patent changes the chemical parameters of the treatment by replacing conventional antihistamines and corticosteroids with a novel mixture of natural extracts (boswellia, blackcurrant, helichrysum, perilla, and quercetin). This parameter change maintains therapeutic effectiveness while eliminating the harmful side effects and drug interactions associated with conventional medications.
Solution Approach 2:
The patent employs a composite material approach by combining multiple natural extracts (boswellia resin, blackcurrant leaves, helichrysum flowering tops, perilla seeds, and quercetin) into a synergistic mixture. This composite formulation achieves the therapeutic effects of conventional medications without their harmful side effects, resolving the contradiction between effectiveness and safety.
2Speed
If conventional pharmacological treatments are used, then immediate symptom relief is achieved, but long-term safety and adaptability are reduced
Solution Approach 1:
The patent changes the temporal parameters of treatment safety by introducing a natural extract mixture that can be used long-term without the cumulative side effects of conventional medications. The formulation maintains rapid symptom relief while enabling extended use across diverse patient populations, including those who cannot tolerate conventional drugs.
Data Source
AI summary
The present invention relates to a mixture comprising or, alternatively, consisting of boswellia, blackcurrant, helichrysum, perilla, quercetin and, optionally, at least one ingredient selected from the group comprising or, alternatively, consisting of a feverfew extract, apple extract, elderberry extract, one or more strains of probiotic bacteria and/or mixtures thereof, useful in the treatment of allergic and/or inflammatory conditions and symptoms, in particular allergic inflammation, on the one hand, and autoimmune and systemic inflammation, on the other. Furthermore, the invention also refers to pharmaceutical compositions and/or compositions for medical devices (Regulation (EU) 2017/745) and/or nutraceuticals and/or food which comprise such novel mixture and to their use in therapy, in the treatment of allergic and/or inflammatory states and symptoms, in particular allergic inflammation, on the one hand, and autoimmune and systemic inflammation, on the other.