Anti-Microbial Composition and Method of Using Same
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Solution Overview
Problem
Current hydrogen peroxide-based antimicrobial compositions have limited efficacy against microorganisms, particularly Clostridium difficile, and often possess an unpleasant odor due to the inclusion of acetic acid or peracetic acid.
Innovation Solution
A composition combining hydrogen peroxide with an organic sulfonic acid and a peroxide adjuvant, such as formic acid or glycolic acid, which enhances antimicrobial activity without the unpleasant odor, achieving at least a 3 log10 reduction in Clostridium difficile spores within a 3-minute contact time.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If hydrogen peroxide is combined with acetic acid and/or peracetic acid to increase effectiveness, then the antimicrobial efficacy is improved, but the composition develops a very unpleasant, pungent odor
Solution Approach 1:
The patent changes the chemical parameters by substituting acetic acid/peracetic acid with formic acid and glycolic acid, which have different chemical properties including lower odor characteristics, while maintaining the desired antimicrobial efficacy through synergistic interactions with hydrogen peroxide
Solution Approach 2:
The patent creates a composite antimicrobial composition combining hydrogen peroxide with formic acid and glycolic acid, where the synergistic interaction between these components achieves enhanced efficacy without the unpleasant odor associated with acetic acid-based formulations
2Object-affected harmful factors
If hydrogen peroxide is used alone as a disinfectant, then the composition is safe and decomposes to oxygen and water, but the rate of biocidal activity is relatively low
Solution Approach 1:
The patent merges hydrogen peroxide with formic acid and glycolic acid to create a synergistic combination where the individual components enhance each other's biocidal activity, achieving a faster rate of action while maintaining the safety profile of hydrogen peroxide decomposition into oxygen and water
3Stability of the object's composition
If traditional hydrogen peroxide compositions are used against Clostridium difficile, then the composition maintains stability, but the efficacy against this pathogen is insufficient
Solution Approach 1:
The patent modifies the chemical composition parameters by adding formic acid and glycolic acid to hydrogen peroxide, creating a formulation that achieves at least a 3 log10 reduction in Clostridium difficile spores within 3 minutes, while the composition remains stable and safe
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively disinfects a broad range of microorganisms, including Clostridium difficile, even at low concentrations, with reduced odor and improved efficacy compared to traditional hydrogen peroxide-based solutions.
Implementation Method 1
Hydrogen peroxide has advantages and benefits to being used as a disinfectant and biocide because it decomposes to oxygen and water
Implementation Method 2
the peroxide source is combined with an organic sulfonic acid and a peroxide adjuvant... achieving at least a 3 log10 reduction after a three minute contact time
Data Source
AI summary
An antimicrobial composition contains hydrogen peroxide, an organic sulfonic acid, and a peroxide adjuvant. The peroxide adjuvant is a small molecule organic acid, such as formic acid. The antimicrobial composition is very effective at sanitizing surfaces in all different types of fields, such as in the healthcare industry. The antimicrobial composition is well suited for controlling C.difficile.