Antidandruff Agent Composite Particles for Scalp Deposition

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Solution Overview

Problem

Existing hair care compositions face challenges in effectively depositing and stabilizing antidandruff agents like piroctone olamine on the scalp due to short contact time and instability in shampoos, leading to insufficient deposition and loss of efficacy over time.

Innovation Solution

The development of composite particles comprising an antidandruff agent, a wax or wax-like substance with a melting point between 30°C to 105°C, and a cationic polymer with a weight average molecular weight of 10^3 to 10^7 Da, which are formulated into microparticles with a size of 0.1 to 1000 microns, and a method of preparing these particles by heating and agitating an aqueous slurry with the addition of a cationic polymer.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If the contact time of hair/scalp with wash-off haircare product is increased to allow sufficient deposition of antidandruff agent, then deposition amount improves, but the product remains on scalp longer causing potential irritation and reduced user convenience

Engineering Contradiction:
Improvedeposition amount of antidandruff agentVSAvoidcontact time on scalp
Core Design Contradiction:
Quantity of substanceVSLoss of time

Solution Approach 1:

The antidandruff agent is pre-complexed with zinc-containing layered material particles before application. This preliminary complexation enhances the deposition efficiency during the brief contact time, allowing sufficient agent deposition without requiring extended contact time on the scalp

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The invention changes the physical-chemical parameters of the antidandruff agent by forming complexes with zinc-containing layered materials. This modification increases the particle size and alters the surface properties, enabling improved deposition during short contact time while maintaining rapid rinse-off characteristics

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If the amount of antidandruff agent is increased to offset wash-off loss, then deposition efficacy improves, but formulation cost and potential scalp irritation increase

Engineering Contradiction:
Improvedeposition amount of antidandruff agentVSAvoidwash-off loss of antidandruff agent
Core Design Contradiction:
Quantity of substanceVSLoss of substance

Solution Approach 1:

The invention creates composite particles by combining antidandruff agent with zinc-containing layered material. This composite structure reduces wash-off loss through enhanced adhesion to scalp and hair, thereby improving deposition efficacy without increasing the amount of active antidandruff agent required

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The zinc-containing layered material acts as an intermediary carrier that facilitates better retention of the antidandruff agent on the scalp. This intermediary structure prevents direct wash-off of the active ingredient while maintaining its antifungal efficacy

Inventive Principle:
Principle #24Intermediary (Mediator)

3Device complexity

If conventional haircare formulations are used without stabilization, then formulation simplicity is maintained, but antidandruff agent stability and efficacy are reduced over time

Engineering Contradiction:
Improveformulation complexityVSAvoidstability of antidandruff agent
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The zinc-containing layered material composite provides a stabilizing matrix that protects the antidandruff agent from degradation by surfactants and other formulation ingredients. This composite approach enhances long-term stability while maintaining relatively simple formulation and processing

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composite particles enhance the deposition and stability of antidandruff agents on the scalp, improving their efficacy and longevity by forming stable microparticles that resist degradation from surfactants and other ingredients, leading to enhanced dandruff control.

Implementation Method 1

composite particles comprising an antidandruff agent, a wax or wax-like substance, and a cationic polymer

Methodology Applied
Scientific EffectElectrostatic interaction: Electrostatics

Implementation Method 2

wax or a wax-like substance in which said antidandruff agent is soluble or dispersible

Methodology Applied
Scientific EffectSolvation: Solvation

Data Source

PatentEP3996663B1Hair care composition comprising antidandruff agent
Publication Date: 2024.08.07 UNILEVER IP HLDG BV
  • EP3996663B1 patent drawing

AI summary

A composition comprising: (i) an antidandruff agent; (ii) a wax or a wax-like substance in which said antidandruff agent is soluble or dispersible, where melting point of said wax and said substance is 30°C to 105°C and where said substance is not a UV absorbing sunscreen; and, (iii) a cationic polymer having weight average molecular weight of 103 Da to 107 Da, where said composition is in the form of particles of particle size 0.1 to 1000 µm and where said wax-like substance is a C13 to 35 fatty alcohol; where said wax is at least one of beeswax, Chinese wax, lanolin, shellac wax, spermaceti, bayberry wax, candelilla wax, carnauba wax, castor wax, esparto wax, Japan wax, ouricury wax, rice bran wax, soy wax, tallow tree wax, ceresin wax, montan wax, ozocerite or peat wax.