Antimethanogenic Compound Extraction and Seed Infusion for Methane Reduction

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Solution Overview

Problem

Current strategies to mitigate methane emissions in ruminant animals face challenges such as unpredictable dosing and efficacy, toxicity, and environmental degradation, undermining widespread adoption and implementation.

Innovation Solution

Development of long-acting compositions and drug delivery devices that infuse antimethanogenic compounds into edible substrates or seeds, providing sustained reduction in methane emissions with lower doses, using encapsulated formulations and controlled release mechanisms.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If current feed additives and chemical inhibitors are used to reduce methane emissions, then methane emissions can be reduced, but the dosing becomes unpredictable and efficacy varies

Engineering Contradiction:
Improvemethane emissionsVSAvoiddosing predictability
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The invention segments the delivery system by infusing antimethanogenic compounds into individual seeds or grains, which are then consumed by ruminant animals. Each seed/grain acts as an independent dosage unit, providing predictable and consistent delivery of the active compound to the rumen environment.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention uses seeds or grains as an intermediary carrier to deliver antimethanogenic compounds to the rumen. The infused seeds/grains serve as a stable medium that protects the compound during storage and transport, then releases it controllably in the rumen environment.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If higher doses of antimethanogenic compounds are administered, then methane emission reduction improves, but toxicity and environmental degradation increase

Engineering Contradiction:
Improvemethane emissionsVSAvoidtoxicity
Core Design Contradiction:
Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The invention optimizes the concentration of antimethanogenic compounds infused into seeds/grains to achieve effective methane reduction at lower overall doses. The controlled release mechanism ensures sustained exposure at therapeutic levels without peak concentrations that cause toxicity.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The infused seeds/grains provide continuous release of antimethanogenic compounds in the rumen environment, maintaining effective concentrations over time without requiring repeated high-dose administrations that would increase toxicity risk.

Inventive Principle:
Principle #20Continuity of useful action

3Object-affected harmful factors

If frequent dosing is performed to maintain efficacy, then methane emission reduction is sustained, but environmental degradation from the dosing ingredients increases

Engineering Contradiction:
Improvemethane emissionsVSAvoidenvironmental degradation
Core Design Contradiction:
Object-affected harmful factorsVSLoss of substance

Solution Approach 1:

The invention uses a single administration of multiple infused seeds/grains that collectively provide sufficient compound delivery for extended periods. This partial dosing approach (single event rather than frequent dosing) achieves sustained efficacy while reducing the cumulative environmental impact of repeated dosing operations.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The antimethanogenic compounds are pre-infused into seeds/grains during manufacturing, creating ready-to-administer units that provide sustained release upon consumption. This preliminary preparation eliminates the need for frequent dosing operations and reduces environmental degradation from repeated handling and administration.

Inventive Principle:
Principle #10Preliminary action

4Reliability

If encapsulated formulations with controlled release mechanisms are used, then dosing predictability and efficacy improve, but device complexity increases

Engineering Contradiction:
Improvedosing predictabilityVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The infused seeds/grains utilize the natural rumen environment (enzymes, moisture, microbial activity) to trigger controlled release of the antimethanogenic compounds. This self-service mechanism eliminates the need for complex external release systems while achieving predictable and sustained dosing.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The seed/grain structure provides natural porosity that allows controlled penetration and release of antimethanogenic compounds in the rumen environment. This inherent porous structure serves as a simple yet effective controlled release mechanism without requiring additional encapsulation layers or complex formulations.

Inventive Principle:
Principle #31Porous materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compositions effectively reduce methane emissions by 50-95% with a single administration, offering prolonged efficacy and minimizing toxicity and environmental impact.

Implementation Method 1

soaking the seed or grain in the antimethanogenic compound, thereby transferring the antimethanogenic compound into the seed's embryo and/or endosperm

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Implementation Method 2

vaporizing the antimethanogenic compound, to create a antimethanogenic compound vapor; contacting the seed or grain with the antimethanogenic compound vapor, thereby infusing the antimethanogenic compound into the seed or grain

Methodology Applied
Scientific EffectVaporization: Evaporation

Implementation Method 3

encapsulated formulations and controlled release mechanisms

Methodology Applied
Scientific EffectControlled release:

Data Source

PatentUS12448600B2Extraction of antimethanogenic compounds
Publication Date: 2025.10.21 SYNERGRAZE INC
  • US12448600B2 patent drawing
  • US12448600B2 patent drawing
  • US12448600B2 patent drawing

AI summary

The present disclosure relates to liquid (e.g., water-soluble) compositions comprising antimethanogenic compounds, and methods of administering the same to reduce enteric methane emissions from ruminant animals, and/or improve feed-efficiency. Certain disclosed compositions exhibit improved rapid effect over prior art compositions. The disclosure further relates to methods of concentrating antimethanogenic compounds, extracting antimethanogenic compounds, and methods of increasing the bioavailability of antimethanogenic compounds.