Antimicrobial Surfactant-Binder Treatment for Wash-Durable Substrates

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Solution Overview

Problem

Current antimicrobial technologies face challenges in maintaining effectiveness against microbial growth and resistance, particularly in fabrics, as they often wash or wear off, leading to instability and potential bacterial resistance.

Innovation Solution

A method involving the use of an antimicrobial surfactant and a polymeric binder, where the substrate is treated with these components under specific conditions such as temperature and pressure to ensure stable incorporation and retention of antimicrobial properties, even after multiple washes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If antimicrobial agents are coated on surfaces, then antimicrobial activity is achieved, but the coating washes or wears off causing loss of effectiveness

Engineering Contradiction:
Improveantimicrobial effectivenessVSAvoiddurability after washing
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent applies preliminary action by embedding the antimicrobial surfactant into the substrate during the manufacturing process rather than coating it afterward. The surfactant is incorporated into the polymer matrix before the substrate is completed, ensuring it becomes an integral part of the material that cannot wash or wear off. This resolves the contradiction by establishing antimicrobial protection at the foundational level rather than as a surface layer.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent creates a composite material system where the antimicrobial surfactant is combined with the substrate material at the molecular level. The surfactant molecules are distributed throughout the polymer matrix, forming a composite structure that maintains antimicrobial activity while benefiting from the mechanical properties of the base material. This composite approach ensures both effectiveness and durability.

Inventive Principle:
Principle #40Composite materials

2Reliability

If conventional antimicrobial compositions are used, then some antimicrobial activity is achieved, but they lead to bacterial resistance and require frequent reapplication

Engineering Contradiction:
Improveantimicrobial activityVSAvoidresistance development
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent changes the fundamental parameter of antimicrobial mechanism from metabolic interference to physical disruption. By using a polycationic surfactant that disrupts microbial membranes through electrostatic interactions and physical lysis rather than metabolic inhibition, the system achieves broad-spectrum activity that does not select for resistant strains. This parameter change in the mode of action resolves the resistance development issue while maintaining reliable antimicrobial activity.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If antimicrobial surfactant and binder are incorporated into substrate, then stable antimicrobial property is achieved, but manufacturing process complexity increases

Engineering Contradiction:
Improvestability of antimicrobial propertyVSAvoidmanufacturing process complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges the antimicrobial surfactant application with the substrate manufacturing process itself. Rather than treating these as separate steps (coating then curing), the surfactant is incorporated into the polymer composition before molding or forming. This consolidation of steps into a single integrated process achieves stable antimicrobial properties without adding manufacturing complexity, as the surfactant incorporation occurs during normal production operations.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method renders substrates stably antimicrobial, achieving a log 4-5 kill rate against various microbes, including bacteria and fungi, while maintaining effectiveness through 50 washes or equivalent exposure, ensuring prolonged protection without inducing bacterial resistance.

Implementation Method 1

contacting the substrate with a polymeric binder; and subjecting the substrate, surfactant, and binder to conditions at which the substrate becomes stably antimicrobial

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Implementation Method 2

polycationic (quaternary ammonium) strings were developed in the laboratory of Robert Engel... These strings are reported to have antibacterial activity

Methodology Applied
Scientific EffectElectrostatic interaction: Electrostatics

Implementation Method 3

Ideally, therefore, novel antimicrobial compositions will function through non-specific, non-metabolic mechanisms

Methodology Applied
Scientific EffectPhysical disruption: Ablation

Data Source

PatentUS9512559B2Method for conferring antimicrobial activity to a substrate
Publication Date: 2016.12.06 RES FOUND THE CITY UNIV OF NEW YORK

AI summary

In one embodiment, the invention relates to a method for rendering a non-metallic substrate stably antimicrobial. The method comprises: (a) contacting the substrate with an antimicrobial surfactant; (b) contacting the substrate with a polymeric binder; and (c) subjecting the substrate, surfactant, and binder to conditions at which the substrate becomes stably antimicrobial. In another embodiment, the invention relates to a substrate into which an antimicrobial surfactant and a binder have penetrated.