Anti-microbial Coating for Multi-dose Container Contamination

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Solution Overview

Problem

Multi-dose cosmetic and fragrance packages face contamination issues due to microbial growth, limited shelf-life, and material permeability, leading to product degradation and safety concerns.

Innovation Solution

Application of an anti-microbial coating on the interior surfaces of packaging, combined with a barrier and pH protective coating, to inhibit microbial growth, extend shelf-life, and prevent material interaction with the contents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If multi-dose packages are used to store products over time, then convenience and reduced waste are improved, but microbial contamination and limited shelf-life worsen

Engineering Contradiction:
Improvemulti-dose convenienceVSAvoidproduct contamination risk
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent applies preliminary anti-action by incorporating preservative systems and barrier coatings into the package design before use. These preventive measures actively counteract microbial contamination from the outset, allowing the product to maintain safety throughout the multi-dose period without requiring user intervention.

Inventive Principle:
Principle #9Preliminary anti-action

Solution Approach 2:

The patent uses intermediary substances such as preservatives (e.g., phenoxyethanol, benzoic acid) and barrier coatings that act as mediators between the product and environmental contaminants. These intermediaries protect the product by blocking or neutralizing harmful microorganisms while allowing the multi-dose package to remain open for repeated use.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If preservatives are added to prevent microbial growth, then product safety is improved, but adverse reactions and product degradation worsen

Engineering Contradiction:
Improvemicrobial protectionVSAvoidadverse user reactions
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by carefully controlling the concentration and combination of preservatives to optimize effectiveness while minimizing adverse reactions. The patent specifies precise ranges for preservative concentrations (e.g., phenoxyethanol at 0.1-1.0%, benzoic acid at 0.05-0.5%) to balance microbial protection with user safety and product stability.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses composite preservative systems combining multiple substances (phenoxyethanol, benzoic acid, sorbic acid, and their salts) that work synergistically to provide broad-spectrum microbial protection while reducing the concentration of each individual component, thereby minimizing adverse reactions and product degradation.

Inventive Principle:
Principle #40Composite materials

3Stability of the object's composition

If barrier coatings are applied to prevent material interaction, then product stability is improved, but gas permeability and manufacturing complexity worsen

Engineering Contradiction:
Improveproduct stabilityVSAvoidcoating system complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The patent applies local quality by applying barrier coatings specifically to the interior surfaces of the package that contact the product, rather than coating the entire package structure. This targeted approach provides necessary protection at the product-coating interface while minimizing overall manufacturing complexity and cost.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent employs relatively simple, cost-effective barrier coating materials that can be applied through standard manufacturing processes. The coatings are designed to provide adequate protection for the product's shelf life without requiring complex multi-layer structures or specialized application equipment, thereby controlling manufacturing complexity.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

4Ease of operation

If applicators are used for precise application, then ease of use is improved, but microbial contamination risk worsens

Engineering Contradiction:
Improveapplication precisionVSAvoidapplicator contamination
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent applies preliminary action by treating the applicator with antimicrobial coatings or incorporating preservatives into the applicator material itself before use. This preventive measure ensures that the applicator remains microbially protected throughout its contact with the product, eliminating the need for user sterilization while maintaining precise application capability.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The anti-microbial coating effectively kills bacteria, extends the post-opening shelf-life of products, and the barrier coating reduces gas permeability, enhancing the pre-opening shelf-life and product stability.

Implementation Method 1

an anti-microbial coating on an interior surface of the one or more walls, wherein the anti-microbial coating is in contact with the fluid; and wherein the anti-microbial coating is effective to kill bacteria introduced into the lumen

Methodology Applied
Scientific EffectAnti-microbial action:

Implementation Method 2

the barrier coating reduces gas permeability, enhancing the pre-opening shelf-life and product stability

Methodology Applied
Scientific EffectPermeability barrier:

Data Source

PatentUS20230242323A1Packages comprising Anti-microbial coatings for preventing contamination, e.g. after first use of the product
Publication Date: 2023.08.03 SIO2 MEDICAL PRODUCTS LLC
  • US20230242323A1 patent drawing
  • US20230242323A1 patent drawing
  • US20230242323A1 patent drawing

AI summary

The present disclosure is directed to multi-dose containers, such as eye drop bottles, nasal spray bottles, cosmetic and fragrance containers, and the like, in which at least a portion of an interior wall of the container, which is in contact with a fluid product, is provided with an anti-microbial coating. The anti-microbial coating is effective to inhibit the growth of microbes and/or inactivate or kill microbes, such as bacteria, that may be introduced into the lumen during use of the product. As such, the shelf life of the product after first use may be increased and/or the amount of preservatives or excipients in the fluid product may be decreased. The containers may also include one or more oxygen barrier coatings, which may increase the shelf life of the product prior to first use.