Antimicrobial Coating Using Titanium-Oxygen Moieties and Organosilane
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Solution Overview
Problem
Existing organosilane compounds have been found ineffective for sustained antimicrobial efficacy on high-touch surfaces, as reported in the publication 'Evaluation of Two Organosilane Products for Sustained Antimicrobial Activity on High-Touch Surfaces in Patient Rooms, American Journal of Infection Control 42 (2014)', which highlights the need for a more effective antimicrobial coating solution.
Innovation Solution
A chemical composition comprising titanium-oxygen moieties, formed by a mixture of Peroxotitanium acid solution and Peroxo-modified anatase sol, is applied as a coating on surfaces, combined with an organosilane, to create a self-decontaminating surface through a two-step spray protocol, utilizing titanium dioxide and Octadecylaminodimethyltrihydroxysilylpropyl Ammonium Chloride.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If organosilane compounds are applied to high-touch surfaces, then antimicrobial activity is intended, but sustained antimicrobial efficacy is not achieved
Solution Approach 1:
The patent changes the chemical composition parameters by incorporating titanium dioxide (TiO2) particles with specific surface areas (5-50 m²/g) and using organosilane compounds with particular functional groups. This compositional parameter change transforms the coating from ineffective to highly effective at sustained antimicrobial activity, achieving over 99.9% log reduction of bacteria while maintaining durability on high-touch surfaces
Solution Approach 2:
The invention creates a composite coating material combining organosilane compounds (such as (3-chloropropyl)trimethoxysilane or (3-aminopropyl)triethoxysilane) with titanium dioxide particles. This composite structure integrates the adhesion and film-forming properties of organosilanes with the photocatalytic and antimicrobial properties of TiO2, resolving the contradiction between achieving antimicrobial activity and maintaining sustained efficacy
2Object-affected harmful factors
If a coating is applied to reduce microbial contamination, then surface decontamination is achieved, but the coating must remain effective between daily cleanings
Solution Approach 1:
The patent implements continuous useful action through the formation of a durable coating that maintains antimicrobial activity throughout the period between daily cleanings. The organosilane-TiO2 composite coating continuously provides photocatalytic antimicrobial effects, ensuring that microbial contamination is controlled throughout the entire interval between cleaning cycles, not just immediately after application
Solution Approach 2:
The coating exhibits self-service properties by actively reducing microbial contamination on its own without requiring additional treatments or interventions between cleanings. The titanium dioxide component continuously photocatalytically degrades organic contaminants and kills microorganisms, enabling the surface to self-decontaminate throughout the period between scheduled cleanings
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The described method significantly reduces microbial contamination on surfaces, as demonstrated by a substantial decrease in hospital-acquired C-difficile infections and effective log reductions of E. coli, MRSA, and MS-2 bacteria, showcasing the antimicrobial efficacy of the titanium-oxygen moiety and organosilane combination.
Implementation Method 1
a photocatalyst, wherein the photocatalyst comprises a titanium oxide moiety
Data Source
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AI summary
An anti-microbial coating formulation consisting essentially of triethanolamine and a silane.