Antimicrobial Composite Material via Chelating Agent Bonding
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Solution Overview
Problem
Existing antimicrobial materials with divalent metal ions are less stable due to environmental factors, leading to shorter antibacterial effective times and reduced stability compared to multivalent metal ions, which are more effective but less stable when physically adsorbed or hydrogen-bonded on porous materials.
Innovation Solution
A method involving a porous material chemically bonded with a chelating agent and a multivalent metal ion, such as silver, cobalt, or nickel, where the metal ion is chemically bonded to the chelating agent, enhancing stability and antibacterial efficacy by forming a more stable antimicrobial composite material.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If multivalent metal ions are physically adsorbed or hydrogen-bonded on porous materials, then antibacterial effectiveness is improved, but stability deteriorates
Solution Approach 1:
The patent creates a composite material structure where porous material serves as the base substrate, chelating agents are chemically bonded to the porous material, and multivalent metal ions are chelated by the chelating agents. This multi-component composite structure enables both high antibacterial effectiveness (from multivalent metal ions) and enhanced stability (from chemical bonding through chelating agents), resolving the contradiction between effectiveness and stability.
Solution Approach 2:
The chelating agent acts as an intermediary between the porous material and the multivalent metal ion. It chemically bonds to the porous material and simultaneously chelates the multivalent metal ion, creating a stable bridge that prevents direct physical adsorption or hydrogen bonding while maintaining close interaction. This intermediary mechanism ensures both stability and antibacterial effectiveness.
2Ease of manufacture
If divalent metal ions are used in antimicrobial materials, then ease of manufacture is improved, but duration of action deteriorates
Solution Approach 1:
The patent changes the valence parameter of the metal ion from divalent to multivalent (trivalent or higher). This parameter change increases the antibacterial effectiveness and duration of action, as multivalent ions have stronger interaction with bacterial cells and longer-lasting effects, while still maintaining reasonable manufacturability through chemical bonding methods.
3Reliability
If antibiotics or organic compounds are used for antimicrobial purposes, then antibacterial effectiveness is improved, but environmental harm increases
Solution Approach 1:
The patent replaces long-lasting organic antimicrobial compounds (which persist in the environment and cause harm) with inorganic multivalent metal ions that can be effectively used and then naturally degrade or dissolve. The porous material with chelating agents provides sustained release, achieving high effectiveness while reducing environmental accumulation and harm compared to traditional organic antimicrobials.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The antimicrobial composite material exhibits a high and long-lasting antibacterial effect, with improved stability and solvent resistance, maintaining antibacterial activity for extended periods, as demonstrated by larger zone of inhibition and lower minimum inhibitory concentration compared to silver nanoparticles and other materials.
Implementation Method 1
a chelating agent chemically bonded to the porous material and a multivalent metal ion chemically bonded to the chelating agent
Implementation Method 2
mixing an oxidizing agent and an ionic compound, wherein the ionic compound has a multivalent metal ion
Data Source
AI summary
An antimicrobial composite material and a method for fabricating the same are provided. The antimicrobial composite material includes a porous material, a chelating agent, and a multivalent metal ion. The chelating agent is chemically bonded to the porous material, and the multivalent metal ion is chemically bonded to the chelating agent.