Antimicrobial Dressing with Perforated Contact Layer for NPWT

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Solution Overview

Problem

Current wound treatment methods face challenges in effectively reducing bio-burden and promoting healing, particularly in managing biofilms and necrotic tissue, which can impede the healing process and require repeated dressing changes, causing discomfort and prolonging recovery.

Innovation Solution

A therapy system incorporating a contact layer with perforations and a film coated with antimicrobial agents like citric acid or acetic acid, which provides negative-pressure therapy and instillation, mechanically disrupting debris while delivering antibacterial agents to the wound site, facilitating pain-free debridement and reducing infection risk.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If repeated dressing changes are performed to manage biofilms and necrotic tissue, then bio-burden reduction is improved, but patient discomfort increases and healing time is prolonged

Engineering Contradiction:
Improvebio-burden reductionVSAvoidhealing time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The dressing is pre-coated with antimicrobial agents (citric acid or acetic acid) before application to the wound site. This preliminary action ensures that the antimicrobial protection is immediately available upon application, eliminating the need for repeated dressing changes to manage biofilms and necrotic tissue, thereby reducing patient discomfort and accelerating healing.

Inventive Principle:
Principle #10Preliminary action

2Object-affected harmful factors

If antimicrobial agents are applied to wound site, then infection risk is reduced, but bio-burden removal efficiency may be compromised

Engineering Contradiction:
Improveinfection riskVSAvoidbio-burden removal efficiency
Core Design Contradiction:
Object-affected harmful factorsVSProductivity

Solution Approach 1:

The dressing combines both antimicrobial protection and mechanical debridement functions in a single integrated system. The antimicrobial-coated film provides infection protection while the foam core with channels enables negative pressure therapy and instillation to mechanically remove bio-burden, achieving both goals simultaneously without compromise.

Inventive Principle:
Principle #5Merging (Combining)

3Productivity

If negative pressure therapy is applied, then tissue growth is accelerated, but debris removal effectiveness may be reduced

Engineering Contradiction:
Improvetissue growth accelerationVSAvoiddebris removal effectiveness
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The foam core is segmented with integrated channels that create multiple pathways for debris removal. This segmentation allows negative pressure to be distributed evenly across the wound site while maintaining effective debris evacuation through the channel network, preventing clogging and ensuring continuous effectiveness.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system enables efficient removal of debris and bio-burden with reduced trauma, promoting healing by combining mechanical disruption with antimicrobial treatment, potentially shortening healing times and minimizing patient discomfort.

Implementation Method 1

The film has an anti-bioburden agent, wherein the anti-bioburden agent comprises citric acid and/or acetic acid

Methodology Applied
Scientific EffectAntimicrobial action:

Implementation Method 2

reducing pressure in proximity to a tissue site can augment and accelerate growth of new tissue at the tissue site

Methodology Applied
Scientific EffectNegative pressure therapy: Pressure Increase

Implementation Method 3

instillation of topical treatment solutions over a wound bed can be combined with negative-pressure therapy to further promote wound healing by loosening soluble contaminants in a wound bed and removing infectious material

Methodology Applied
Scientific EffectFluid instillation:

Data Source

PatentEP4007550B1Antimicrobial/antibacterial disruptive dressing for use with negative pressure and fluid instillation
Publication Date: 2024.11.27 SOLVENTUM INTELLECTUAL PROPERTIES CO
  • EP4007550B1 patent drawingFigure 1
  • EP4007550B1 patent drawingFigure 2
  • EP4007550B1 patent drawingFigure 3

AI summary

Dressings, systems, and methods for treating a tissue site are described herein. The dressing has a contact layer having a plurality of holes. The contact layer is configured to be positioned adjacent to the tissue site. The dressing also includes a cover layer having a first side configured to be positioned adjacent to the contact layer and a second side opposite the first side. An antimicrobial agent is coupled to the first side of the cover layer. The dressing has a drape configured to be positioned over the cover layer to form a sealed space having the contact layer and the cover layer disposed in the sealed space.