Fabric compositions comprising attached ascorbic acid

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Solution Overview

Problem

Current antimicrobial textiles face challenges in achieving effective, long-lasting, and environmentally friendly antimicrobial and antiviral properties, particularly in medical and hygiene applications, where synthetic agents are not ideal due to toxicity and resistance concerns, and naturally occurring compounds like ascorbic acid have shown limited efficacy when used alone.

Innovation Solution

Development of antimicrobial and antiviral fabric compositions comprising ascorbic acid, citric acid, and sodium hypophosphite covalently attached to cellulosic portions of fabrics, utilizing a pad/spray drying method and curing process to generate hydrogen peroxide for antimicrobial activity, enhancing the fabric's ability to inhibit microbial growth and viral activity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If ascorbic acid is applied alone to textiles, then the fabric remains non-toxic and environmentally friendly, but the antimicrobial activity is insufficient

Engineering Contradiction:
Improveantimicrobial activityVSAvoidmicrobial growth inhibition
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent combines ascorbic acid with citric acid and sodium hypophosphite to create a synergistic antimicrobial system. This merging of multiple natural compounds achieves effective antimicrobial activity (99.99% inhibition) while maintaining the non-toxic and environmentally friendly properties of natural substances, resolving the contradiction between sufficient antimicrobial efficacy and environmental safety.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite antimicrobial system where ascorbic acid, citric acid, and sodium hypophosphite work together on cellulosic fabrics. This composite approach leverages the complementary properties of each component to achieve robust antimicrobial and antiviral activity that none of the individual substances could provide alone, while preserving biocompatibility.

Inventive Principle:
Principle #40Composite materials

2Reliability

If synthetic antimicrobial agents are used in textiles, then effective antimicrobial activity is achieved, but toxicity and antibiotic resistance concerns arise

Engineering Contradiction:
Improveantimicrobial activityVSAvoidtoxicity and resistance
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent employs naturally occurring compounds (ascorbic acid, citric acid, sodium hypophosphite) that degrade into harmless substances, replacing persistent synthetic antimicrobials. These natural compounds provide effective antimicrobial activity while being non-toxic and non-resistant, effectively treating the fabric as a disposable or short-lived antimicrobial system that leaves no harmful residue.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The invention converts the limitations of natural compounds (individually weak antimicrobial activity) into a benefit through combination therapy. By merging multiple natural substances, the system achieves synthetic-level efficacy while maintaining the inherent safety and biodegradability of natural products, turning what was a weakness into a strength.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

3Object-affected harmful factors

If ascorbic acid is used in medical textiles, then non-toxic properties are maintained, but the duration of antimicrobial effectiveness is limited

Engineering Contradiction:
ImprovetoxicityVSAvoidantimicrobial effectiveness duration
Core Design Contradiction:
Object-affected harmful factorsVSDuration of action of stationary object

Solution Approach 1:

The patent achieves continuous antimicrobial action by creating a sustained-release system where ascorbic acid, citric acid, and sodium hypophosphite are incorporated into the fabric structure. This combination provides prolonged effectiveness (72-96 hours) while maintaining non-toxic properties, ensuring continuous protection without requiring frequent reapplication or causing tissue damage.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The approach results in fabrics with up to 99.99% inhibition of microbial growth and significant antiviral activity, providing a robust, non-toxic, and sustainable solution for medical textiles that can maintain effectiveness for extended periods without tissue breakdown, suitable for wound dressings and barrier fabrics.

Implementation Method 1

utilizing a pad/spray drying method and curing process to generate hydrogen peroxide for antimicrobial activity

Methodology Applied
Scientific EffectHydrogen peroxide generation: Chemical Bonding

Implementation Method 2

enhancing the fabric's ability to inhibit microbial growth and viral activity

Methodology Applied
Scientific EffectAntimicrobial activity: Oxidation

Implementation Method 3

ascorbic acid is covalently attached to at least one cellulosic portion of the fabric composition

Methodology Applied
Scientific EffectCovalent bonding: Chemical Bonding

Data Source

PatentUS20220323635A1Fabric compositions comprising attached ascorbic acid
Publication Date: 2022.10.13 THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
  • US20220323635A1 patent drawing
  • US20220323635A1 patent drawing
  • US20220323635A1 patent drawing

AI summary

The invention relates to antimicrobial and/or antiviral fabric compositions comprising ascorbic acid, citric acid, sodium hypophosphite, or a mixture thereof. The ascorbic acid may be covalently attached to at least one cellulosic portion of the fabric composition. The invention also relates to methods for preparing such fabric compositions.