Antimicrobial ionomer composition and uses thereof

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Solution Overview

Problem

Current antimicrobial technologies, particularly those using silver, face challenges such as the potential hazards of nanoparticulate silver and limited development of polymer carrier-based silver technologies, along with issues like discoloration and particle formation in existing compositions.

Innovation Solution

Development of an antimicrobial ionomer composition comprising an amine functional cationic polymer, specifically poly(ethyleneimine) with a molecular weight between 200 and 3,000,000, reacted with silver halides or non-halide silver salts, and stabilized with sulfonamide group-containing substances, which provides enhanced adhesion, antimicrobial activity, and controlled silver-ion release.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If nanoparticulate silver is used for antimicrobial applications, then antimicrobial activity is improved, but health and environmental hazards increase

Engineering Contradiction:
Improveantimicrobial activityVSAvoidhealth and environmental hazards
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The invention extracts only the beneficial antimicrobial property of silver (ionic silver release) while eliminating the harmful nanoparticle form. By using silver salts that release ionic silver controlled by the polymer matrix, the patent achieves antimicrobial activity without the health and environmental risks associated with nanoparticulate silver.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The invention changes the physical and chemical parameters of silver delivery from nanoparticulate form to ionic form released from a polymer matrix. This parameter change transforms silver from a potentially hazardous nanoparticle into a controlled ionic release system that maintains antimicrobial efficacy while reducing hazards.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If conventional silver containing particles are attached to surfaces, then antimicrobial activity is achieved, but particle formation and stability issues occur

Engineering Contradiction:
Improveantimicrobial activityVSAvoidparticle stability and discoloration
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The invention creates a composite material system where a polymer matrix (polymer carrier) is combined with silver salts. This composite structure integrates the silver within the polymer network, preventing particle formation and discoloration while maintaining controlled ionic silver release for antimicrobial activity.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The polymer matrix acts as an intermediary between the silver source and the environment. It mediates the release of ionic silver, preventing direct particle formation and stabilizing the composition against discoloration while enabling controlled antimicrobial action.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If polymer carrier based silver technologies are developed, then adhesion and controlled release are improved, but technological maturity is limited

Engineering Contradiction:
Improveadhesion and controlled releaseVSAvoidtechnological development stage
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The invention segments the silver delivery system into distinct functional components: a polymer matrix for adhesion and structural support, and silver salts for antimicrobial activity. This segmentation allows independent optimization of each component and simplifies the manufacturing process compared to integrated nanoparticle systems.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The polymer-silver salt composition is designed to be self-sufficient, where the polymer matrix inherently provides adhesion to substrates and controlled release of ionic silver without requiring additional complex manufacturing steps or specialized equipment. The system serves its own functions of attachment and regulated delivery.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition offers improved antimicrobial efficacy, optical performance, and stability, with enhanced adhesion properties and controlled silver-ion release, surpassing existing compositions, and is suitable for various surfaces and applications without particle formation.

Implementation Method 1

the lone pair electrons of nitrogen atoms of amine compounds with high boiling point or water-soluble polymer with basic nitrogen at the backbone or side chain are coordinated with silver ion

Methodology Applied
Scientific EffectCoordination:

Implementation Method 2

reacting poly(ethyleneimine) having a molecular weight (Mw) between 200 and 3,000,000 and a silver halide

Methodology Applied
Scientific EffectIon exchange: Ion Exchange

Implementation Method 3

reacting poly(ethyleneimine) having a molecular weight (Mw) between 200 and 3,000,000 and at least one silver non-halide salt or complex compound and hydrogen halide or an alkali metal or alkaline earth metal or ammonium halide salt

Methodology Applied
Scientific EffectDissolution: Solvation

Data Source

PatentEP2773197B1Antimicrobial ionomer composition and uses thereof
Publication Date: 2017.10.04 NOLLA ANTIMICROBIAL LTD

AI summary

The invention concerns a polymeric antimicrobial composition, a method of producing the same and the uses thereof. The ionomer composition comprises an amine functional polymer compound reacted with silver halide, optionally together with a stabilizing component, such as an organic substance carrying a sulfonamide functional group. The ionomer composition can be obtained by reacting together (i) at least one polyamine and silver halide and optionally at least one organic stabilizer substance or; (ii) at least one polyamine, at least one non-halide silver salt or silver complex, hydrogen halide and/or alkaline metal halide salt and optionally at least one organic stabilizer substance. The present ionomer composition is suitable for use as an antimicrobial coating, antimicrobial finish, antimicrobial additive and as antimicrobial component for formation of new antimicrobial materials.