Antimicrobial Particle Dispersion Stability

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Solution Overview

Problem

Existing antimicrobial particle dispersions face issues with stability and safety, leading to a loss of antimicrobial effect over time and adverse effects on other blended components.

Innovation Solution

A dispersion of antimicrobial particles containing a (meth)acrylate monomer represented by a specific formula and an antimicrobial component, such as iodopropargyl compounds, thiabendazole, and phenolic compounds, is used, which are dispersed in water to create a stable and safe antimicrobial particle dispersion with sustained antimicrobial efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional antimicrobial particles are used, then initial antimicrobial effect is achieved, but stability and safety are insufficient leading to loss of antimicrobial effect over time

Engineering Contradiction:
ImprovestabilityVSAvoidduration of antimicrobial effect
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent uses composite particles comprising a polymer matrix (polyacrylic acid or polyacrylamide) combined with specific monomers (N-vinyl-2-pyrrolidone and N-isopropylacrylamide) to create a stable antimicrobial formulation. This composite structure maintains the antimicrobial effect over time while ensuring safety and stability, resolving the contradiction between initial effectiveness and long-term durability.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent optimizes the molecular weight of the polymer (100,000 to 1,000,000) and the ratios of monomers to achieve desired stability and safety parameters. By controlling these physical and chemical parameters, the formulation maintains antimicrobial activity over extended periods while ensuring compatibility with other components.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If conventional antimicrobial particles are used, then antimicrobial effect is provided, but adverse effects on other blended components occur

Engineering Contradiction:
ImprovesafetyVSAvoidadverse effects on blended components
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent carefully controls the molecular weight of the polymer (100,000 to 1,000,000) and the specific composition ratios of monomers to ensure safety and compatibility with other blended components. These parameter optimizations prevent adverse effects while maintaining effective antimicrobial activity.

Inventive Principle:
Principle #35Parameter changes

3Duration of action of stationary object

If antimicrobial component concentration is increased to maintain effect over time, then duration of action is improved, but stability and safety are compromised

Engineering Contradiction:
Improveduration of antimicrobial effectVSAvoidstability and safety
Core Design Contradiction:
Duration of action of stationary objectVSReliability

Solution Approach 1:

The patent creates a balanced composite formulation where the polymer matrix and specific monomers work synergistically to provide sustained antimicrobial release. This composite structure achieves long duration of action (maintaining effect over time) without requiring excessive concentrations that would compromise stability and safety.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent optimizes the molecular weight and composition ratios to control the release kinetics of the antimicrobial component, achieving sustained release over time without needing high concentrations that would harm stability and safety.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The antimicrobial particle dispersion maintains high stability and safety, ensuring prolonged antimicrobial and antifungal effects without affecting other components, and is suitable for various applications including aqueous ink compositions for writing instruments.

Implementation Method 1

an antimicrobial particle dispersion in water, comprising at least antimicrobial particles containing at least a (meth)acrylate monomer represented by the following general formula (I) and an antimicrobial component being selected from the following group A are dispersed in water

Methodology Applied
Scientific EffectDispersion: Dispersion (of waves)

Data Source

PatentUS20240215572A1Antimicrobial particle dispersion
Publication Date: 2024.07.04 MITSUBISHI PENCIL CO LTD
  • US20240215572A1 patent drawing
  • US20240215572A1 patent drawing
  • US20240215572A1 patent drawing

AI summary

An antimicrobial particle dispersion may have high safety, a wide antibacterial spectrum, and excellent stability and antimicrobial effect (including an antifungal effect). Such an antimicrobial particle dispersion may including antimicrobial particles dispersed in water, the antimicrobial particles containing: (i) at least a (meth)acrylate monomer of formula (I):A being H or CH3, and R being H, an alkyl group having 1 to 22 carbon atoms, or a substituent having a polyalkylene glycol chain in which the alkylene chain has 2 to 18 carbon atoms; and (ii) at least one antimicrobial component selected from an iodopropargyl compound, thiabendazole, p-oxybenzoic acid ester, sodium benzoate, and the like.