Antimicrobial Polymer Concentrates Surface Migration

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Solution Overview

Problem

Existing antimicrobial plastic articles face challenges in achieving desired efficacy due to regulatory restrictions on antimicrobial ingredient usage and difficulty in effectively inhibiting both gram-positive and gram-negative bacteria, particularly in achieving at least a log 2 antimicrobial efficacy.

Innovation Solution

Incorporating a migratory assisting agent into antimicrobial masterbatches that carries antimicrobial agents to the surface of plastic articles, enhancing both initial and sustained antimicrobial effectiveness by improving the distribution and concentration of antimicrobial agents at the surface.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If regulatory restrictions on antimicrobial ingredient usage are followed, then safety and compliance are improved, but antimicrobial efficacy deteriorates

Engineering Contradiction:
Improvesafety and complianceVSAvoidantimicrobial efficacy
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies local quality by concentrating the antimicrobial agent at the surface of the polymer article rather than uniformly distributing it throughout the bulk material. The migratory assisting agent facilitates this localized concentration at the surface, enabling high antimicrobial efficacy where needed while keeping the overall concentration of antimicrobial ingredients low to meet regulatory requirements.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The migratory assisting agent serves as an intermediary substance that carries the antimicrobial agent from the polymer matrix to the surface. This mediator enables the antimicrobial agent to reach its effective location without requiring high overall concentrations, thus resolving the contradiction between compliance and efficacy.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Quantity of substance

If antimicrobial agents are restricted to low concentrations, then regulatory compliance is improved, but ability to inhibit both gram-positive and gram-negative bacteria deteriorates

Engineering Contradiction:
Improveantimicrobial ingredient concentrationVSAvoidbacterial inhibition capability
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The invention achieves broad-spectrum bacterial inhibition at low concentrations by localizing the antimicrobial agent at the surface through the migratory assisting agent. This surface concentration strategy enables effective inhibition of both gram-positive and gram-negative bacteria while maintaining low overall ingredient levels for regulatory compliance.

Inventive Principle:
Principle #3Local quality

3Ease of manufacture

If antimicrobial agents are uniformly distributed in the polymer, then manufacturing simplicity is improved, but surface antimicrobial performance deteriorates

Engineering Contradiction:
Improvemixing and processing simplicityVSAvoidsurface antimicrobial performance
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The migratory assisting agent acts as a mediator that simplifies manufacturing by being mixed uniformly with the polymer and antimicrobial agent, yet subsequently directs the antimicrobial agent to the surface during processing and use. This approach maintains manufacturing simplicity while achieving superior surface performance.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The migratory assisting agent is pre-incorporated into the polymer matrix during manufacturing, establishing a mechanism that will automatically transport the antimicrobial agent to the surface later. This preliminary action during manufacturing enables subsequent surface localization without adding complex post-processing steps.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The use of migratory assisting agents in antimicrobial masterbatches significantly improves the antimicrobial efficacy of plastic articles, achieving enhanced log reductions for both gram-positive and gram-negative bacteria, often with reduced amounts of antimicrobial agents, as demonstrated by the JIS Z 2801 test method.

Implementation Method 1

the migratory assisting agent transfers or 'migrates' to the surface of the polymer compound or article. As a result, antimicrobial agents are brought to the surface

Methodology Applied
Scientific EffectMigration: Diffusion

Data Source

PatentUS10051867B2Antimicrobial polymer concentrates and compounds
Publication Date: 2018.08.21 AVIENT CORP

AI summary

Migratory assisting agents are used to improve antimicrobial efficacy of antimicrobial masterbatches, the polymer compounds these antimicrobial masterbatches are let down into, and the articles made therefrom. The migratory assisting agents function by carrying the antimicrobial agents while the migratory assisting agent transfers or “migrates” to the surface of a polymer compound or article formed from the polymer compound. As a result, antimicrobial agents are brought to the surface where there is exposure to bacterial contamination.