Antioxidant Composition for Preventing Lipid Oxidation Odor

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Solution Overview

Problem

Middle-aged and elderly individuals often experience a characteristic body odor known as 'old person smell' due to the degradation of lipid hydroperoxides in their skin, releasing compounds like 2-nonenal, which existing fragrances cannot effectively prevent or reduce.

Innovation Solution

The use of specific chemical compounds such as α-oxocarboxylic acids, their salts, thiols, sulfur-containing peptides, and ascorbic acid derivatives in personal care products and laundry care products to prevent the formation or reduce the intensity of malodorous compounds by chemically consuming organic hydroperoxides.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If fragrances are applied to cover-up old person smell, then the unpleasant odor is masked temporarily, but the underlying chemical compounds (2-nonenal and other lipid oxidation products) continue to form and the fragrance itself may eventually oxidize and deteriorate

Engineering Contradiction:
Improveold person smellVSAvoidduration of odor control
Core Design Contradiction:
Object-affected harmful factorsVSDuration of action of stationary object

Solution Approach 1:

The patent converts the harmful lipid hydroperoxides into beneficial products by using antioxidants (vitamin C, vitamin E, ferulic acid, resveratrol) to reduce them to non-odorous alcohols. This transforms the oxidation process from harmful (producing 2-nonenal) to beneficial (producing non-odorous reduced compounds), thereby eliminating the root cause rather than masking symptoms

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent applies antioxidants to skin and personal care products before lipid oxidation can proceed to form malodorous compounds. By pre-establishing a protective antioxidant environment, the oxidation of skin lipids is prevented at the hydroperoxide stage, stopping the formation pathway before 2-nonenal and other unpleasant odorants are generated

Inventive Principle:
Principle #10Preliminary action

2Object-affected harmful factors

If antioxidants are used to prevent lipid oxidation, then the formation of malodorous compounds is reduced, but the antioxidants themselves may degrade over time reducing their effectiveness

Engineering Contradiction:
Improvemalodorous compound formationVSAvoidantioxidant effectiveness
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent combines multiple antioxidants (vitamin C, vitamin E, ferulic acid, resveratrol) into a synergistic formulation where each component supports and enhances the others. This composite antioxidant system provides more reliable and sustained protection against lipid oxidation compared to single antioxidants, as the degradation of one component is compensated by the others

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent employs antioxidants that can regenerate each other through redox cycles. For example, vitamin E can be regenerated by vitamin C, creating a feedback loop that maintains antioxidant activity. This self-replenishing mechanism ensures sustained effectiveness and extends the functional life of the antioxidant system in preventing malodorous compound formation

Inventive Principle:
Principle #23Feedback

3Object-affected harmful factors

If conventional deodorants are used to mask body odor, then the odor is temporarily covered, but they do not address the root cause (lipid hydroperoxide degradation) and may provide false security

Engineering Contradiction:
Improvebody odorVSAvoidsimplicity of solution
Core Design Contradiction:
Object-affected harmful factorsVSEase of manufacture

Solution Approach 1:

Instead of masking the harmful effects of lipid oxidation with fragrances, the patent converts the harmful oxidation process into a beneficial reduction process. The antioxidants transform lipid hydroperoxides into non-odorous alcohols, directly eliminating the source of body odor rather than concealing it, providing a scientifically sound and effective solution

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

These compounds effectively mitigate the formation of malodorous aldehydes, providing a more pleasant body odor and extending the shelf life of perfumes and food products by reducing the peroxide value, thereby addressing the issue of 'old person smell' and rancidity.

Implementation Method 1

the chemical compounds that create the malodor are prevented from forming, reduced in intensity, and/or ameliorated... chemically consuming organic hydroperoxides

Methodology Applied
Scientific EffectOxidation-reduction reaction: Redox Reactions

Implementation Method 2

hydrolysable esters of 2-oxoacids, glyoxylic acids, and/or oxalic acids to produce a controlled and/or extended in-situ release of a 2-oxoacid, oxalic acid monoester, or oxalic acid via chemical or enzymatic hydrolysis/cleavage

Methodology Applied
Scientific EffectHydrolysis: Hydrolysis

Data Source

PatentUS20230210735A1Prevention, reduction, or amelioration of old person smell
Publication Date: 2023.07.06 FIRMENICH SA
  • US20230210735A1 patent drawing
  • US20230210735A1 patent drawing
  • US20230210735A1 patent drawing

AI summary

The various aspects presented herein relate to methods and compositions for the reduction, prevention, and/or inhibition of old person smell.