Antioxidant Formulation Using Composite Natural Ingredients

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Solution Overview

Problem

Existing antioxidant medicaments for cardiovascular diseases in elderly patients are limited due to contraindications, particularly the increase in arterial tension caused by eleutherococcus in known compositions.

Innovation Solution

A novel antioxidant formulation comprising pollen, royal jelly, vitamin C, vitamin E, and dihydroquercetin, with excipients, in specific weight ratios, forming tablets that provide comprehensive antioxidative protection without the adverse effects of eleutherococcus, suitable for elderly individuals.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If eleutherococcus is included in the antioxidant formulation, then immunity is improved and antioxidant action is enhanced, but arterial tension increases which contraindicates use in elderly patients with cardiovascular diseases

Engineering Contradiction:
Improveimmunity enhancementVSAvoidarterial tension increase
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent removes eleutherococcus from the formulation while retaining other beneficial components (pollen, royal jelly, vitamins C and E, propolis). This extraction eliminates the harmful effect of increased arterial tension while preserving the antioxidant and immunomodulating properties through alternative natural ingredients.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent creates a composite formulation combining multiple natural ingredients (pollen, royal jelly, propolis, vitamins C and E, dihydroquercetin) that work synergistically to provide antioxidant protection and immunity enhancement without the adverse cardiovascular effects of eleutherococcus. The composite approach distributes the functional benefits across several components.

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If the antioxidant formulation uses only natural ingredients, then safety and tolerability are improved, but the range of effective antioxidants is limited

Engineering Contradiction:
Improvesafety and tolerabilityVSAvoidrange of antioxidants
Core Design Contradiction:
Object-affected harmful factorsVSAdaptability or versatility

Solution Approach 1:

The patent combines multiple natural antioxidants (vitamins C and E, propolis, pollen, royal jelly, dihydroquercetin) in a composite formulation to achieve a broad spectrum of antioxidant activity. This approach maintains the safety and tolerability of natural ingredients while expanding the versatility through synergistic interactions among different natural compounds.

Inventive Principle:
Principle #40Composite materials

3Reliability

If the formulation includes multiple active ingredients in optimal ratios, then therapeutic effectiveness is improved, but manufacturing complexity increases

Engineering Contradiction:
Improvetherapeutic effectivenessVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent specifies precise weight ratios for each ingredient (e.g., vitamin C: 10-50 mg, vitamin E: 5-20 mg, propolis: 50-200 mg, pollen: 100-500 mg, royal jelly: 10-50 mg, dihydroquercetin: 10-30 mg) to optimize therapeutic effectiveness. These parameter specifications provide clear manufacturing guidelines that balance effectiveness with manufacturability.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP2514429B1antioxidant
Publication Date: 2018.03.07 OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTJU PARAFARM

AI summary

The invention relates to the chemico-pharmaceutical industry, specifically to the production of an antioxidant. The antioxidant comprises the following ingredients: flower pollen, dihydroquercetin, vitamin C, vitamin E, honeybee royal jelly and fillers. The antioxidant produced provides all the nutrients necessary for an organism in microdoses and ensures antioxidant protection from external adverse factors.