Expandable Aortic Occluding Surface for False Lumen Blockage
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Solution Overview
Problem
Aortic dissection leads to the formation of a false lumen in the aorta, causing competition for blood flow between the true and false lumens, which can result in impaired perfusion of vital structures, and existing treatments are inadequate in effectively blocking blood flow through the false lumen.
Innovation Solution
An implantable expandable device with an occluding surface oriented in a transverse plane, bounded by lateral and medial occluding surface edges with specific radii of curvature, and a supporting structure of struts, which can be expanded to block blood flow in the superior-inferior direction within the false lumen.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional stent placement is used to treat aortic dissection, then the true lumen can be supported, but the false lumen blood flow cannot be effectively blocked
Solution Approach 1:
The device divides the occlusion function into two distinct components: an occluding surface for blocking the false lumen and a supporting structure for maintaining the true lumen. This segmentation allows each component to be optimized for its specific function, achieving effective false lumen occlusion without compromising true lumen patency.
Solution Approach 2:
The occluding surface extends into the false lumen space, creating a three-dimensional occlusion barrier rather than relying solely on radial compression. This dimensional approach enables effective blood flow blocking while maintaining structural support for the true lumen.
2Reliability
If an expandable device is deployed to occlude the false lumen, then blood flow blocking is achieved, but the device must be navigated through the vasculature in a collapsed state
Solution Approach 1:
The device transitions from a collapsed, flexible state for delivery through the vasculature to an expanded, rigid state for occlusion. This dynamic transformation enables the device to navigate tortuous anatomy and then provide stable, effective false lumen blocking upon deployment.
Solution Approach 2:
The occluding surface is nested within or attached to the supporting structure, allowing the entire device to be compressed into a small delivery profile while maintaining the functional integrity of both components during deployment.
Data Source
AI summary
An implantable expandable device includes an occluding surface oriented substantially in a transverse plane. The occluding surface is bounded by a lateral occluding surface edge and a medial occluding surface edge. The occluding surface has an occluding surface body located transversely between the lateral and medial occluding surface edges. A supporting structure is located entirely inferiorly to the occluding surface. The supporting surface includes a plurality of struts extending substantially in the superior-inferior direction. At least a first one of the struts is a full-height strut and spans substantially a full superior-inferior height of the device. At least a second one of the struts is a reduced-height strut and spans substantially less than a full superior-inferior height of the device. The occluding surface substantially occludes a transverse cross-section of the false lumen to substantially block bloodflow in the superior-inferior direction within the false lumen.