Cylindrical Apatite/Collagen Composite Bone Implant
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Solution Overview
Problem
Existing artificial bones, particularly those made of hydroxyapatite ceramics, are difficult to handle due to their hardness and brittleness, and lack sufficient mechanical strength for use in stress-bearing body parts, despite having excellent tissue penetrability and bone conduction.
Innovation Solution
A cylindrical apatite/collagen composite with a hollow center and pores of 100-1000 μm diameter is developed, which is formed by rolling a sheet-shaped apatite/collagen composite, providing sufficient strength and tissue penetrability, and can be absorbed and replaced by autogenous bone.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If hydroxyapatite ceramics are used for artificial bone, then bone conduction and tissue penetrability are improved, but handling difficulty increases due to hardness and brittleness
Solution Approach 1:
The patent uses an apatite/collagen composite material that combines the bone-conductive properties of hydroxyapatite with the flexibility and ease of handling of collagen. This composite structure allows the material to be manipulated during surgery while maintaining excellent bone conduction and tissue penetrability, resolving the contradiction between reliability and ease of operation.
2Reliability
If hydroxyapatite ceramics are used for artificial bone, then bone conduction is improved, but mechanical strength is insufficient for stress-bearing parts
Solution Approach 1:
The apatite/collagen composite combines the high bone conduction of hydroxyapatite with the mechanical strength and flexibility of collagen. This composite structure enables the material to withstand stress while maintaining excellent bone conduction properties, solving the contradiction between reliability and strength.
Solution Approach 2:
The patent employs a porous structure in the apatite/collagen composite that enhances both mechanical strength and bone conduction. The porous architecture allows for stress distribution while maintaining pathways for bone ingrowth, thereby improving both strength and reliability simultaneously.
3Reliability
If a wave-sheet-shaped hydroxyapatite/collagen composite with hollow portion is used, then tissue penetrability is improved, but strength decreases
Solution Approach 1:
The patent uses a porous apatite/collagen composite structure that provides excellent tissue penetrability while maintaining sufficient strength. The controlled porosity allows tissue infiltration without compromising the mechanical integrity of the implant, resolving the contradiction between reliability and strength.
Solution Approach 2:
The apatite/collagen composite material combines the bone-conductive porous structure with the mechanical strength of collagen, enabling the material to simultaneously achieve excellent tissue penetrability and sufficient strength for load-bearing applications.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The artificial bone achieves mechanical properties comparable to living bones, allowing for effective bone repair and replacement, reducing the burden on patients and surgeons by eliminating the need for autogenous bone grafting.
Implementation Method 1
a cylindrical body obtained by rolling a sheet-shaped apatite/collagen composite
Implementation Method 2
it has disadvantageously low strength despite excellent tissue penetrability and bone conduction
Implementation Method 3
penetrating pores formed on a peripheral surface to permit cells and tissues to enter
Implementation Method 4
which is absorbed (biodegraded) and replaced by an autogenous bone when implanted in the body
Data Source
AI summary
An artificial bone capable of being absorbed and replaced by an autogenous bone, which comprises a cylindrical body obtained by rolling a sheet-shaped apatite/collagen composite, a hollow center portion of the cylindrical body penetrating from one end surface to the other end surface having a diameter of 100-1000 μm.