Aprotic Solvent Stabilization of Hydrolytically Unstable Benefit Agents

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Solution Overview

Problem

Benefit agents in compositions are susceptible to hydrolysis during storage, leading to breakdown and instability, which affects consumer experience by providing unpredictable performance.

Innovation Solution

Incorporating an aprotic solvent with a molecular weight between 70 and 250, specifically propylene glycol carbonate, to stabilize benefit agents with hydrolytically or nucleophilically unstable bonds in detergent compositions, along with detergent adjunct ingredients.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If benefit agents are used in compositions, then consumer desired benefits are provided, but the benefit agents are susceptible to hydrolysis during storage

Engineering Contradiction:
Improvebenefit agent stabilityVSAvoidhydrolysis susceptibility
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

An aprotic solvent is introduced as an intermediary substance between the benefit agent and water to prevent direct contact and hydrolysis. The aprotic solvent forms a protective environment that mediates the interaction between the benefit agent and the aqueous phase, thereby preventing hydrolytic degradation while maintaining product functionality.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The chemical environment parameters are changed by selecting solvents with specific properties (aprotic character, molecular weight between 70-250). This parameter change transforms the solvent environment from hydrolytically active to hydrolytically inert, thereby stabilizing the benefit agent against degradation.

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If benefit agents with hydrolytically unstable bonds are used, then desired consumer benefits are achieved, but breakdown occurs during storage

Engineering Contradiction:
Improvebenefit agent functionalityVSAvoidcomposition stability
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The aprotic solvent acts as a mediator that allows the benefit agent to maintain its functional properties while preventing hydrolytic breakdown. The intermediary creates a stable chemical environment that preserves both the functionality and compositional integrity of the benefit agent throughout storage.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If benefit agents are used in product, then consumer desired performance is provided, but performance becomes unpredictable during product lifetime

Engineering Contradiction:
Improveperformance consistencyVSAvoidproduct lifetime performance
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The aprotic solvent is incorporated into the formulation in advance to prevent hydrolysis before it can occur during storage. This preliminary protective action ensures that the benefit agent remains stable throughout the entire product lifetime, maintaining consistent performance from manufacture through use.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The use of aprotic solvents significantly improves the stability of benefit agents, ensuring consistent performance across the product's lifetime by preventing hydrolysis, thereby enhancing consumer satisfaction.

Implementation Method 1

an aprotic solvent, preferably wherein the aprotic solvent has a molecular weight of between 70 and 250

Methodology Applied
Scientific EffectSolvation: Solvation

Implementation Method 2

the benefit agent comprises at least one hydrolytically unstable bond

Methodology Applied
Scientific EffectHydrolysis prevention: Hydrolysis

Data Source

PatentUS9540601B2Composition comprising benefit agent and aprotic solvent
Publication Date: 2017.01.10 PROCTER & GAMBLE CO
  • US9540601B2 patent drawing
  • US9540601B2 patent drawing
  • US9540601B2 patent drawing

AI summary

Composition comprising a benefit agent and an aprotic solvent, wherein the benefit agent comprises at least one hydrolytically unstable bond, or at least one nucleophilically unstable bond, or a mixture thereof. Methods of making such compositions.