Active Physiological System for Metabolic Syndrome Treatment

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Solution Overview

Problem

Current treatments for metabolic syndrome are multifactorial and difficult to manage, often leading to iatrogenic disorders due to polypharmacy, with limited effectiveness in addressing the syndrome's complexity and high side effects, while traditional therapies focus on individual symptoms rather than systemic rebalancing.

Innovation Solution

A mixture comprising 56% to 84% dietary fibers, with 31% to 47% soluble and 25% to 37% insoluble fibers, vegetable fats, phenols, terpenes, sugars, and inorganic compounds, forming an Active Physiological System (APS) that interacts with the intestine to slow nutrient absorption, reduce fat and carbohydrate absorption, and promote metabolic rebalancing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If polypharmacy is used to treat individual metabolic imbalances, then specific symptoms can be addressed, but the treatment complexity increases and iatrogenic disorders occur

Engineering Contradiction:
Improveeffectiveness of treating metabolic syndromeVSAvoidtreatment complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple dietary components (resistant starch, soluble fibers, insoluble fibers, plant sterols, polyphenols, and probiotics) into a single integrated dietary intervention. This unified approach addresses multiple metabolic imbalances simultaneously through one cohesive system rather than requiring separate treatments for each symptom, thereby reducing treatment complexity while maintaining comprehensive effectiveness.

Inventive Principle:
Principle #5Merging (Combining)

2Reliability

If polypharmacy is used to treat metabolic syndrome, then individual symptoms can be addressed, but side effects increase

Engineering Contradiction:
Improveeffectiveness of treating metabolic syndromeVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent employs food-based interventions using naturally occurring dietary components rather than synthetic pharmaceuticals. These dietary elements are inherently safe, biodegradable, and compatible with human physiology, eliminating the harmful side effects associated with long-term pharmaceutical use while maintaining therapeutic effectiveness for metabolic syndrome management.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Ease of operation

If traditional therapies focus on individual symptoms, then specific alterations can be treated, but the systemic complexity of metabolic syndrome is not addressed

Engineering Contradiction:
Improvesimplicity of treatment approachVSAvoidability to address metabolic syndrome complexity
Core Design Contradiction:
Ease of operationVSAdaptability or versatility

Solution Approach 1:

The patent creates a multi-functional dietary system where a single intervention simultaneously addresses multiple aspects of metabolic syndrome including insulin resistance, dyslipidemia, hypertension, and visceral obesity. The combined dietary components work synergistically to improve various metabolic parameters concurrently, providing a versatile solution that adapts to the systemic complexity of the syndrome while maintaining operational simplicity for the patient.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The APS system effectively reduces glycemic and lipemic peaks, normalizes intestinal transit, and rebalances metabolic parameters without causing side effects, providing a systemic approach to treating metabolic syndrome while being environmentally friendly and biodegradable.

Implementation Method 1

A mixture comprising from 56% to 84% w/w of dietary fibers, wherein from 31% to 47% w/w of said mixture is represented by soluble fibers and from 25% to 37% w/w of said mixture is represented by insoluble fibers

Methodology Applied
Scientific EffectGel formation: Gel

Implementation Method 2

slowing down and reduces the absorption of lipids and carbohydrates

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Implementation Method 3

normalizes intestinal transit

Methodology Applied
Scientific EffectViscosity change: Viscoelasticity

Data Source

PatentUS20230354869A1New system with emerging properties for use in the treatment of metabolic syndrome
Publication Date: 2023.11.09 ABOCA S P A SOC AGRI
  • US20230354869A1 patent drawing
  • US20230354869A1 patent drawing
  • US20230354869A1 patent drawing

AI summary

The present invention provides a new system with emerging properties in the form of a mixture or composition and the use of the same in the treatment or in assisting the treatment of the metabolic syndrome or one or more symptoms related to it.