Aqueous Composition Vesicle Oil Drop Stability

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Solution Overview

Problem

Conventional methods fail to stably coexist vesicles and oil drops in an aqueous composition, limiting skin compatibility and moistness due to poor emulsification and limited oil incorporation.

Innovation Solution

A production method involving an amphiphilic compound, an aqueous component, and oil, where the amphiphilic compound forms vesicles and includes a silicone surfactant with HLB of 4 to 12, and hydrocarbon oil, allowing for the separation of oil drops and vesicles, enhanced by anionic or silicone surfactants with HLB greater than 12 for improved stability and skin compatibility.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If a large amount of oil is blended into the aqueous composition containing vesicles, then the oil content increases, but emulsification occurs and vesicle formation becomes infeasible

Engineering Contradiction:
Improveoil contentVSAvoidvesicle stability
Core Design Contradiction:
Quantity of substanceVSStability of the object's composition

Solution Approach 1:

The invention divides the oil phase into two distinct components: oil incorporated within the vesicle membrane (forming part of the vesicle structure) and oil separated as distinct drops in the aqueous phase. This segmentation allows both vesicles and free oil drops to coexist stably without emulsification, resolving the contradiction between high oil content and vesicle stability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention changes the physical and chemical parameters of the system by selecting specific amphiphilic compounds with appropriate HLB values (4-12) and using oils with specific properties (hydrocarbon oil, silicone oil, or polar oil with IOB 0.05-0.8). These parameter changes enable the system to accommodate large amounts of oil while maintaining vesicle integrity and preventing emulsification.

Inventive Principle:
Principle #35Parameter changes

2Stability of the object's composition

If only a small amount of oil is contained inside the vesicle membrane, then vesicle stability is maintained, but the blending quantity of oil is limited and moistness provision is difficult

Engineering Contradiction:
Improvevesicle stabilityVSAvoidoil blending quantity
Core Design Contradiction:
Stability of the object's compositionVSQuantity of substance

Solution Approach 1:

The invention transitions from a single-phase vesicle system to a multi-phase system where oil exists in two dimensions: incorporated within the vesicle membrane and separated as external oil drops in the aqueous phase. This dimensional expansion allows the system to achieve both vesicle stability and high overall oil content by utilizing both intra-vesicular and extra-vesicular oil reservoirs.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Quantity of substance

If an emulsion composition with sufficient oil is used, then oil content increases, but compatibility and non-stickiness are compromised

Engineering Contradiction:
Improveoil contentVSAvoidskin compatibility
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The invention uses amphiphilic compounds (silicone surfactants with HLB 4-12, anionic surfactants, or their combinations) as intermediary substances that enable the coexistence of oil drops and vesicles in the aqueous phase. These intermediaries stabilize the interface between oil and water phases, prevent emulsification, and maintain skin compatibility by controlling the physical state and distribution of oil in the composition.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method enables an aqueous composition with excellent skin compatibility and moist feeling by stabilizing vesicles and oil drops, allowing for a higher oil content without compromising skin non-stickiness or causing oiliness, and maintaining stability over time.

Implementation Method 1

Some of amphiphilic compounds having both hydrophilicity and hydrophobicity form a bilayer membrane (lamellar phase) spherical structure in an aqueous phase. Such a small sphere having the bilayer membrane structure is called a liposome or a vesicle

Methodology Applied
Scientific EffectVesicle formation: Self-Assembly

Implementation Method 2

oil (c) as oil separating from a vesicle-formable amphiphilic compound under mixing

Methodology Applied
Scientific EffectPhase separation: Emulsion

Data Source

PatentEP2990025B1Aqueous composition
Publication Date: 2019.10.09 SHISEIDO CO LTD
  • EP2990025B1 patent drawingFigure 1
  • EP2990025B1 patent drawingFigure 2
  • EP2990025B1 patent drawingFigure 3(A)~3(B)

AI summary

The present invention provides an aqueous composition in which vesicles and oil drops are stably coexistent. The aqueous composition of the present invention is characterized by containing (a) an amphiphilic compound, (b) water, and (c) oil, wherein vesicles formed with component (a) and oil drops containing component (c) are present in component (b).