Aqueous Extraction Process for Bioactive Plant Compounds

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Solution Overview

Problem

Existing methods for extracting key compounds from specific plants are inadequate for producing a chemical composition with the desired health benefits, such as treating cancer, inflammation, hair loss, and boosting immunity, due to inefficiencies in the extraction process.

Innovation Solution

An aqueous extraction process using a combination of Cinnamomum cassia, Arctium lappa, Vitex agnus castus, Lonicera japonica, Acanthopanax gracilistylis, Raphanus sativus, Astragalus membranaceus, and Hordeum vulgare, involving a static or dynamic system with reverse-osmosis filtered water and heat, to produce a biologically active extract with enhanced bioavailability and bioactivation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional extraction methods are used, then the extraction process is simple, but the chemical composition cannot reliably produce the desired health benefits

Engineering Contradiction:
Improvereliability of producing chemical composition with health benefitsVSAvoidcomplexity of extraction process
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent changes multiple extraction parameters including using aqueous solvent instead of organic solvents, controlling pH levels, adjusting temperature profiles, and modifying extraction time to optimize the release of bioactive compounds while maintaining safety and effectiveness

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent incorporates preliminary steps such as drying and grinding plant materials to specific specifications, pre-treating the plant material, and preparing extraction buffers before the main extraction process to ensure consistent and reliable results

Inventive Principle:
Principle #10Preliminary action

2Reliability

If conventional extraction methods are used, then the process is straightforward, but bioavailability and bioactivation are insufficient

Engineering Contradiction:
Improvebioavailability and bioactivationVSAvoidease of extraction process
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent modifies extraction parameters including pH adjustment, temperature control, and solvent composition to enhance the bioavailability of extracted compounds and promote their bioactivation in the body

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses specific excipients and carriers as intermediaries to facilitate the absorption and bioactivation of extracted compounds, improving their biological activity without complicating the overall manufacturing process

Inventive Principle:
Principle #24Intermediary (Mediator)

3Object-affected harmful factors

If existing extraction methods are used, then the process is simple, but side effects cannot be reduced

Engineering Contradiction:
Improveside effectsVSAvoidextraction process complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent adjusts extraction parameters such as pH, temperature, and solvent composition to selectively extract beneficial compounds while excluding harmful substances, thereby reducing side effects through precise control of the extraction process

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent selectively extracts only the beneficial bioactive compounds from plant materials while leaving behind potentially harmful substances, effectively separating the useful components from harmful ones in the extraction process

Inventive Principle:
Principle #2Taking out (Extraction)

4Productivity

If conventional methods are used, then the extraction is straightforward, but productivity is insufficient

Engineering Contradiction:
Improveextraction efficiencyVSAvoidextraction system complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent implements continuous extraction processes where solvent circulation is maintained throughout, ensuring continuous contact between solvent and plant material to maximize extraction efficiency and productivity

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The patent employs hydraulic systems for continuous solvent circulation and pressure-driven extraction, utilizing fluid dynamics to enhance extraction speed and efficiency while maintaining controlled conditions

Inventive Principle:
Principle #29Pneumatics and hydraulics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The process yields a chemical composition with significant health benefits, including anti-cancer, anti-inflammatory, energy-boosting, and immune-boosting properties, with reduced side effects and increased bioavailability, effectively addressing various human health issues.

Implementation Method 1

an aqueous extraction process using a combination of Cinnamomum cassia, Arctium lappa, Vitex agnus castus, Lonicera japonica, Acanthopanax gracilistylis, Raphanus sativus, Astragalus membranaceus, and Hordeum vulgare, involving a static or dynamic system with reverse-osmosis filtered water and heat

Methodology Applied
Scientific EffectAqueous extraction: Solvation

Implementation Method 2

reverse-osmosis filtered water

Methodology Applied
Scientific EffectReverse osmosis: Reverse Osmosis

Implementation Method 3

involving a static or dynamic system with reverse-osmosis filtered water and heat

Methodology Applied
Scientific EffectThermal energy: Heating

Data Source

PatentUS11622987B2Aqueous extraction process of plants, method thereof, and product by process
Publication Date: 2023.04.11 EIR PHARMACEUTICALS LLC
  • US11622987B2 patent drawing
  • US11622987B2 patent drawing
  • US11622987B2 patent drawing

AI summary

The preparation of an aqueous extract resulting from an aqueous extraction process of Cinnamomum aromaticum, Arctium lappa, Viticis fructus, Lonicera japonica, Acanthopanax gracilistylis, Raphanus sativus, Astragalus membranaceus and Hordeum vulgare and the chemical composition comprising said extract or fraction thereof, and the use of said composition or fraction thereof for treating or preventing cancers and inflammation related diseases, hair loss, stimulating hair growth, increasing energy production, and boosting immunity.