Articulating Mesh for Bifurcation Aneurysm Flow Diversion
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Solution Overview
Problem
Current flow-diverting devices for treating bifurcation aneurysms often fail to adequately cover the neck of the aneurysm, leading to inadequate blood flow diversion and potential arterial occlusion or stroke, especially when used at bifurcation points where they disrupt blood flow to adjacent vessels.
Innovation Solution
The development of an expandable mesh device with circumferentially discontinuous articulating portions that can be positioned at angles relative to a tubular body portion, allowing the device to be placed across the neck of a bifurcation aneurysm, effectively blocking blood flow into the aneurysm while permitting flow to branching vessels, utilizing slits and radiopaque markers for precise placement and visualization.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a tubular flow-diverting device is placed across the neck of a bifurcation aneurysm, then blood flow into the aneurysm is blocked, but blood flow to the adjacent branching vessel is disrupted
Solution Approach 1:
The device is divided into multiple articulated segments that can be independently positioned. The distal articulating portion can be oriented at an angle to extend into the branching vessel while the proximal portion remains in the parent vessel, allowing selective coverage of the aneurysm neck without blocking the branch vessel lumen
Solution Approach 2:
The device incorporates articulating portions that can rotate and adjust their orientation relative to the tubular body portion. This dynamic capability allows the device to adapt to the bifurcation geometry and orient the articulating portion at optimal angles to cover the aneurysm neck while preserving blood flow to the branching vessel
2Reliability
If an intrasaccular occlusive device is positioned within the aneurysm, then blood flow into the aneurysm is reduced, but the device may relocate out of the aneurysm into the vessel
Solution Approach 1:
The flow-diverting device is deployed in advance to cover the aneurysm neck and create a barrier that prevents intrasaccular devices from herniating or relocating into the parent or branching vessels. This preliminary protective action stabilizes the position of subsequently deployed occlusive devices within the aneurysm sac
3Reliability
If a flow-diverting device with low porosity is used, then blood flow into the aneurysm is effectively blocked, but the device structure becomes more complex
Solution Approach 1:
The device is segmented into a tubular body portion and articulating portions, with the low porosity mesh concentrated in the regions needed for flow diversion (proximal and distal ends) while the articulating portions have higher porosity to reduce complexity and facilitate navigation through vessels
Data Source
AI summary
Expandable devices are disclosed herein. Several of the embodiments are directed towards an expandable device comprising a mesh configured to be expanded at a blood vessel bifurcation of a human patient. The mesh may comprise a tubular body portion and one or more circumferentially discontinuous articulating portions. The mesh may be expanded such that the one or more articulating portions are positioned at an angle to the tubular body portion.