Aryl Ether Compounds for Broad-Spectrum Crop Protection

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Solution Overview

Problem

Current fungicides and insecticides lack efficacy at low dosages and have limited spectrum of activity against various plant diseases and insects, requiring higher application rates and often failing to control a wide range of pathogens and pests effectively.

Innovation Solution

Development of aryl ether compounds with specific structural formulas that exhibit broad-spectrum fungicidal and insecticidal activity, allowing for effective control of diseases caused by oomycete, basidiomycete, ascomycete, and deuteromycete pathogens, as well as insect control, at very low dosages due to high activity and penetration capabilities.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional fungicides and insecticides are applied at higher dosages, then the control efficacy against plant diseases and insects is improved, but the application cost and environmental burden increase

Engineering Contradiction:
Improvecontrol efficacyVSAvoidapplication dosage
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent applies parameter changes by modifying the chemical structure parameters of fungicides and insecticides through specific substitution patterns on the pyrazole and triazole rings. By changing parameters such as the type of substituent groups (halo, alkyl, alkoxy, etc.) and their positions, the compounds achieve enhanced biological activity and better penetration capabilities, allowing effective control at lower dosages

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs composite materials by designing compounds with multiple functional groups combined in a single molecular structure. The fungicides and insecticides contain composite structures including pyrazole or triazole rings with various substituent groups (halo, alkyl, alkoxy, carboxyl, etc.), creating molecules that simultaneously possess multiple biological activities and improved penetration properties

Inventive Principle:
Principle #40Composite materials

2Adaptability or versatility

If conventional fungicides and insecticides are used, then some plant diseases and insects are controlled, but the spectrum of activity is limited and cannot effectively control a wide range of pathogens and pests

Engineering Contradiction:
Improvespectrum of activityVSAvoidcontrol efficacy
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent applies universality by designing compounds that can control multiple types of plant diseases and insects simultaneously. The fungicides and insecticides with specific structural formulas exhibit broad-spectrum activity against various pathogens (oomycete, basidiomycete, ascomycete, deuteromycete) and insect pests, allowing a single compound to perform multiple protective functions

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent uses parameter changes to achieve broad-spectrum activity by systematically varying the substituent groups and their positions on the core molecular structure. By adjusting parameters such as the type of heteroatom (O, S, or NR2), the nature of substituent groups (halo, alkyl, alkoxy, etc.), and their spatial arrangement, the compounds achieve versatility against different pathogens and pests while maintaining high efficacy

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS7786045B2Aryl ether compounds and their preparation and use thereof
Publication Date: 2010.08.31 SHENYANG SINOCHEM AGROCHEMICALS R&D CO LTD
  • US7786045B2 patent drawing
  • US7786045B2 patent drawing
  • US7786045B2 patent drawing

AI summary

The invention relates to aryl ether compounds and its preparation method and use thereof. The aryl ether compounds of the invention having general formula (I):The groups are as defined as specification. The aryl ether compounds of present invention have wide spectrum fungicidal activity, and may be used to control diseases in all sorts of plants caused by oomycete, basidiomycete, ascomycete pathogens and deuteromycete. The some of the compounds have very good insecticidal and acaricidal activity, and may be used to control insects and mites.