Ascorbic Acid 2-Glucoside Amino Acid Salt Stability

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Solution Overview

Problem

Ascorbic acid 2-glucoside undergoes browning reactions, which are not sufficiently suppressed by existing methods, affecting its stability and effectiveness in cosmetic and other compositions.

Innovation Solution

The formation of ascorbic acid 2-glucoside basic amino acid salts, such as lysine, arginine, and histidine salts, which inhibit browning reactions, providing improved stability and skin compatibility.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If ascorbic acid 2-glucoside is used instead of ascorbic acid, then stability is improved, but browning reaction still occurs

Engineering Contradiction:
ImprovestabilityVSAvoidbrowning reaction
Core Design Contradiction:
Stability of the object's compositionVSObject-generated harmful factors

Solution Approach 1:

The patent uses ascorbic acid 2-glucoside as an intermediary compound that converts to ascorbic acid in the body, providing the desired antioxidant effects while avoiding the direct instability and browning issues of pure ascorbic acid. This intermediary approach resolves the contradiction by delivering benefits indirectly through metabolic conversion.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates a composite system by combining ascorbic acid 2-glucoside with other stabilizing components and delivery systems, forming a composite material that enhances overall stability while preventing browning reactions. This composite approach allows the beneficial properties to be maintained while mitigating the harmful browning effect.

Inventive Principle:
Principle #40Composite materials

2Reliability

If ascorbic acid is used in high concentration, then effectiveness is improved, but skin irritation increases

Engineering Contradiction:
ImproveeffectivenessVSAvoidskin irritation
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

Ascorbic acid 2-glucoside serves as a gentler intermediary that converts to active ascorbic acid in the skin, providing high concentration effectiveness without the direct irritation caused by pure ascorbic acid. The glucoside form is less irritating while maintaining the ability to deliver high levels of active vitamin C through metabolic conversion.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the chemical parameter of ascorbic acid by converting it to its 2-glucoside derivative form. This parameter change modifies the properties to reduce skin irritation while preserving the ability to provide high concentration effectiveness through in vivo conversion to the active form.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If ascorbic acid is used in aqueous solution, then usability is improved, but oxidation occurs rapidly

Engineering Contradiction:
ImproveusabilityVSAvoidoxidation resistance
Core Design Contradiction:
Ease of operationVSStability of the object's composition

Solution Approach 1:

The patent uses ascorbic acid 2-glucoside as a stable intermediary that can be formulated in aqueous solutions without rapid oxidation. This intermediary form maintains stability in aqueous environments while still providing the ability to convert to active ascorbic acid when needed, resolving the contradiction between aqueous usability and oxidation resistance.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent performs preliminary conversion of ascorbic acid to its 2-glucoside form before formulation, which preemptively prevents oxidation issues in aqueous solutions. This preliminary action stabilizes the compound for aqueous formulation while preserving the ability to deliver active ascorbic acid through subsequent metabolic conversion.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The ascorbic acid 2-glucoside basic amino acid salts significantly suppress browning, maintaining the antioxidant and collagen-promoting effects of ascorbic acid while ensuring stable storage and reduced skin irritation, making them suitable for high-concentration use in cosmetics and pharmaceuticals.

Implementation Method 1

ascorbic acid 2-glucoside basic amino acid salts significantly suppress browning, maintaining the antioxidant and collagen-promoting effects

Methodology Applied
Scientific EffectBrowning reaction inhibition: Oxidation

Implementation Method 2

Ascorbic acid acts as a reducing agent, a collagen synthesis promoter, and an antioxidant, and in particular, the excellent antioxidant effect of ascorbic acid is known as a component that suppresses the generation of melanin in the skin

Methodology Applied
Scientific EffectReducing agent action: Reduction

Data Source

PatentUS20250017841A1Compound containing ascorbic acid derivative
Publication Date: 2025.01.16 DRS CHOICE CO LTD
  • US20250017841A1 patent drawing
  • US20250017841A1 patent drawing
  • US20250017841A1 patent drawing

AI summary

The present invention relates to a browning-suppressed composition containing ascorbic acid 2-glucoside basic amino acid salt. Blending of the ascorbic acid 2-glucoside basic amino acid salt makes it possible to suppress browning of the composition.