Aseptic Airlock Transfer with Adjustable Volume Decontamination

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Solution Overview

Problem

Existing methods for transferring objects under aseptic conditions from an airlock into a process chamber are inefficient and require significant technical effort to adapt to varying requirements.

Innovation Solution

A method involving a pressure-tight transfer unit with a housing that surrounds an airlock chamber with a pressure-tight transfer unit connected to the airlock, utilizing a housing with a pressure-tight sealable entrance gate, an outlet for objects, an inlet for decontamination agents, and a lockable transfer door, with specific steps for decontamination and transfer.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of time

If the airlock chamber volume is minimized to match the object volume, then the decontamination time is reduced and decontamination agent diffusion is minimized, but the flexibility to accommodate different object sizes is reduced

Engineering Contradiction:
Improvedecontamination timeVSAvoidflexibility to accommodate different object sizes
Core Design Contradiction:
Loss of timeVSAdaptability or versatility

Solution Approach 1:

The airlock chamber volume is made dynamically adjustable through movable walls that can be positioned to match the volume of objects to be transferred. This allows the airlock chamber to adapt its size to different object dimensions, minimizing free volume for each specific transfer operation, thereby reducing decontamination time and agent diffusion while maintaining flexibility for various object sizes.

Inventive Principle:
Principle #15Dynamics

2Productivity

If the airlock chamber is designed for minimal volume to reduce decontamination agent diffusion, then transfer efficiency is improved, but the device complexity increases due to adjustable volume mechanisms

Engineering Contradiction:
Improvetransfer efficiencyVSAvoidadjustable volume mechanisms
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The airlock chamber incorporates movable walls with adjustable positions that can be configured to match the volume of objects to be transferred. This dynamic volume adjustment capability allows the system to minimize free airlock volume for each specific transfer operation, thereby improving transfer efficiency by reducing decontamination time and agent diffusion, while the mechanism itself remains relatively simple and integrated into the chamber structure.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method minimizes the free airlock volume, allowing rapid decontamination and transfer of objects, thereby minimizing the diffusion of decontamination agents and allowing flexible design to meet varying requirements.

Implementation Method 1

The decontamination agent in the airlock chamber is atomized, e.g. by means of a two-fluid nozzle or by ultrasound

Methodology Applied
Scientific EffectUltrasound: Ultrasound

Data Source

PatentEP4656209A1Method for transferring objects from a lock into the working chamber of a containment under aseptic conditions
Publication Date: 2025.12.03 SKAN
  • EP4656209A1 patent drawingFigure 1A~1C
  • EP4656209A1 patent drawingFigure 2A~2C
  • EP4656209A1 patent drawingFigure 3A~3C

AI summary

The present invention relates to a method for transferring objects (4) under aseptic conditions from an airlock (3) into the process chamber (21) of a containment (2), which is surrounded by a housing (20) and forms a pressure-tight transfer unit (1) with the airlock (3). A housing (30) of the airlock (3) surrounds an airlock chamber (31) with the airlock volume (VS). The airlock chamber (31) has a pressure-tight closable entrance gate (37) which, when open, allows access (33) from the outer installation room (A) for introducing objects (4) into the airlock chamber (31). Furthermore, the airlock (3) has an outlet (38) which is intended for transferring the objects (4) from the airlock chamber (31) into the process chamber (21). Furthermore, the lock (3) has an inlet (34) for introducing decontamination agents.