Aspartic Acid Feed Additives for Better Feed Conversion
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Solution Overview
Problem
Existing animal feed additives do not effectively improve production performance in farmed animals, particularly in terms of growth and feed conversion efficiency.
Innovation Solution
The use of N-carbamoyl aspartic acid derivatives, including racemates, stereoisomers, geometric isomers, tautomers, solvates, and feed-acceptable salts, in animal feed additives, which are formulated into feed compositions to enhance animal production performance.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If conventional animal feed additives are used, then feed intake is maintained, but production performance and growth are not effectively improved
Solution Approach 1:
The patent changes the chemical structure parameters of traditional feed additives by introducing N-carbamoyl aspartic acid derivatives with specific molecular structures (Formula I), where R1, R2, R3, and R4 can be various substituents including hydrogen, alkyl groups, aryl groups, and heteroatom-containing groups. This structural parameter modification enables the additive to effectively improve production performance and growth in farmed animals.
Solution Approach 2:
The patent creates a composite feed additive system by combining N-carbamoyl aspartic acid core structure with various substituent groups (R1-R4) that can include amino acids, peptides, or other functional groups. This composite approach enhances the biological activity and effectiveness of the feed additive, resolving the issue of insufficient improvement in production performance.
2Productivity
If traditional feed additives are used, then basic nutrition is provided, but feed conversion efficiency remains suboptimal
Solution Approach 1:
The patent modifies the molecular parameters of feed additives by using N-carbamoyl aspartic acid derivatives with tunable R groups (R1-R4) that can be configured to optimize nutrient absorption. The general formula allows systematic variation of physical and chemical parameters to enhance feed conversion efficiency while controlling feed intake levels.
3Productivity
If feed additives are administered to improve growth, then average daily gain increases, but feed intake also increases
Solution Approach 1:
The patent employs N-carbamoyl aspartic acid derivatives with specific substituent patterns (R1-R4 groups) that modify the biological activity parameters of the feed additive. These parameter changes enable the additive to stimulate growth and increase average daily gain without proportionally increasing feed intake, thereby improving growth efficiency.
Data Source
AI summary
Disclosed herein is use of an aspartic acid derivative having a structure represented by formula (I), or a racemate, stereoisomer, geometric isomer, tautomer, solvate or feed-acceptable salt thereof, in preparing an animal feed additive that significantly improves production performance of farmed animals,wherein each of Y and X is independently a C1-C20 alkyl or H; R1 is R1aC(═O) or H; R2 is R2aC(═O); and each of R1a and R2a is independently (A)(B)N—(CH2)0-5—, and each of A and B is independently a C1-C20 alkyl or H.