Aspiration Device with Dynamic Pressure Control for Lesion Removal

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Solution Overview

Problem

Existing aspiration methods for removing foreign substances from blood vessels, such as thrombi, face challenges in efficiently aspirating materials based on the state of the lesion, as the aspiration pressure and flow rates are not adequately controlled to match the specific conditions of the lesion.

Innovation Solution

An aspiration device with a pump and controller that can apply negative pressure and select between constant and variable pressure modes based on the length and occlusion rate of the lesion, using imaging data from X-ray and ultrasound devices to determine the appropriate aspiration mode and flow rates for efficient removal.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If constant pressure aspiration is applied to all lesions, then the device is simple to operate, but aspiration efficiency varies according to lesion state

Engineering Contradiction:
Improveaspiration operation simplicityVSAvoidaspiration efficiency
Core Design Contradiction:
Ease of operationVSProductivity

Solution Approach 1:

The aspiration device transitions from static constant pressure operation to dynamic variable pressure operation. The controller automatically adjusts aspiration pressure based on real-time feedback from pressure sensors and lesion characteristics, enabling the system to adapt to different lesion states (occlusion rate, length) and maximize aspiration efficiency for each specific case.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system changes the aspiration pressure parameter dynamically based on lesion characteristics. By measuring lesion length and occlusion rate, the controller selects optimal pressure parameters from predefined sets or calculates them in real-time, ensuring that the aspiration pressure matches the specific requirements of each lesion type.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If variable pressure aspiration is applied to match lesion state, then aspiration efficiency is improved, but device complexity increases

Engineering Contradiction:
Improveaspiration efficiencyVSAvoidaspiration control system complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The aspiration device incorporates a feedback control system where pressure sensors continuously monitor the aspiration pressure and lesion characteristics. This feedback information is processed by the controller, which automatically adjusts the pump output to maintain optimal aspiration conditions, reducing the need for manual intervention and simplifying the user interface despite the complex internal control mechanisms.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system performs self-adjustment of aspiration parameters based on automatically acquired lesion data. The controller independently determines the optimal aspiration mode (constant or variable pressure) and parameters without requiring manual input from the operator, making the complex system easy to use while maintaining high aspiration efficiency.

Inventive Principle:
Principle #25Self-service

3Productivity

If high aspiration pressure is applied to remove foreign substances quickly, then removal speed is improved, but blood flow disruption increases

Engineering Contradiction:
Improveforeign substance removal speedVSAvoidblood flow disruption
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The aspiration device applies different pressure levels to different segments of the lesion based on local characteristics. By dividing the lesion into segments with different occlusion rates and lengths, the system applies optimized pressure to each segment, achieving effective foreign substance removal while minimizing overall blood flow disruption through localized pressure control.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device effectively controls aspiration by varying pressure and flow rates to enhance the removal efficiency of foreign substances, minimizing blood flow disruptions and promoting deformation and removal of thrombi, regardless of lesion length and occlusion rates.

Implementation Method 1

a pump connectable to an aspiration catheter and capable of applying a negative pressure to the aspiration catheter

Methodology Applied
Scientific EffectNegative pressure: Pressure Gradient

Data Source

PatentUS20240008885A1Aspiration device, aspiration system, and aspiration method
Publication Date: 2024.01.11 TERUMO KK
  • US20240008885A1 patent drawing
  • US20240008885A1 patent drawing
  • US20240008885A1 patent drawing

AI summary

An aspiration device for aspirating an object in a blood vessel, includes a pump connectable to an aspiration catheter and capable of applying a negative pressure to the aspiration catheter, and a controller configured to: acquire a length of an abnormal part of the blood vessel in which the object exists and an occlusion rate of the abnormal part, select either a first aspiration mode in which the pressure applied to the aspiration catheter is maintained at a certain level or a second aspiration mode in which the pressure is varied, and control the pump to apply the pressure according to the selected aspiration mode.