Aspiration Tip Plunger Air Extraction
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Solution Overview
Problem
Conventional aspiration tips face challenges in accurately and efficiently aspirating and discharging small amounts of viscous liquids or cell cultures due to air volume fluctuations, leading to decreased efficiency and sample contamination.
Innovation Solution
The aspiration tip features a syringe section with a tubular passage and a plunger that moves to discharge air before aspiration, ensuring no air intervenes during the process, allowing for precise and efficient aspiration and discharge of small volumes by maintaining contact with the inner wall to prevent residual samples.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If air is present in the tubular passage during aspiration and discharge, then the conventional aspiration tip can operate with simple structure, but volume fluctuations occur due to air expansion and contraction, reducing aspiration and discharge accuracy
Solution Approach 1:
The invention extracts and eliminates air from the tubular passage by introducing a plunger that pushes against the liquid column to discharge air before aspiration. This removes the harmful factor (air) that causes volume fluctuations, thereby improving measurement precision without significantly complicating the device structure.
Solution Approach 2:
The plunger performs a preliminary action by discharging air from the tubular passage before the actual aspiration process begins. This preliminary removal of air prevents subsequent volume fluctuations during aspiration and discharge, ensuring accurate measurement from the start.
2Reliability
If air is discharged and re-introduced during aspiration and discharge, then the conventional aspiration tip can be operated repeatedly, but sample contamination occurs between successive samples
Solution Approach 1:
The plunger extracts and removes air from the tubular passage, creating a sealed liquid column that prevents sample contamination. This allows repeated operations without introducing contaminants, maintaining sample purity while enabling continuous use of the aspiration tip.
3Measurement precision
If air remains in the tubular passage during observation, then the observation system can be simple, but observation accuracy is reduced
Solution Approach 1:
The plunger removes air from the tubular passage, creating a clear liquid-filled path that improves observation accuracy. The extracted air is discharged, leaving only the liquid and sample visible for observation, thereby enhancing measurement precision.
4Quantity of substance
If the aspiration tip uses pressure fluctuations from air movements to aspirate and discharge objects, then the operation mechanism can be simple, but very small amounts of objects cannot be aspirated and discharged efficiently and accurately
Solution Approach 1:
The invention replaces the air-pressure fluctuation mechanism with a direct mechanical plunger system that pushes against the liquid column. This mechanical substitution eliminates the inefficiencies of air compression and expansion, enabling precise and efficient handling of very small liquid volumes through direct contact and controlled displacement.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This design enhances the accuracy and efficiency of aspirating and discharging small volumes, reducing contamination and maintaining high observation accuracy, especially for biological cells and cell aggregations.
Implementation Method 1
a plunger (160) movable back and forth while coming in contact with an inner wall surface of the syringe section (110)... generating an aspiration force in the tubular passage to aspirate the object
Implementation Method 2
a pump mechanism is driven to generate an aspiration force in the tubular passage to aspirate the object
Data Source
Figure 1
Figure 2
Figure 3A~3B
AI summary
An aspiration tip is provided with: a syringe section including an inner tubular passage defining an aspiration path for aspirating an object; and a plunger movable in the tubular passage while coming in contact with an inner wall surface of the tubular passage, wherein the syringe section includes an aspiration opening formed in a distal end of the tubular passage for aspirating the object, and the plunger includes a plunger leading end portion configured to protrude from the aspiration opening before the aspiration of the object and at the time of discharge of the object, and retract in the syringe section at the time of the aspiration of the object.