Asymmetric-Load Support Assembly for Multi-Sample Conditioning

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Multi-sample conditioning systems face mechanical imbalances when sample chambers are removed or when samples of different stiffness are conditioned together, leading to undesired alterations in the conditioning profile and increased variation in nutrient flow, which can result in biased statistical analysis and reduced actuator lifespan.

Innovation Solution

An asymmetric-load support assembly with a low-friction, high-rigidity flexure is introduced to maintain the support rod's centerline, reducing lateral displacement and opposing rotation caused by asymmetric loading, thereby maintaining a consistent conditioning profile across samples.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If multiple samples are conditioned together in a multi-sample conditioning system, then statistical analysis capability is improved, but mechanical imbalance occurs when samples of different stiffness are conditioned together or when sample chambers are removed

Engineering Contradiction:
Improvestatistical analysis capabilityVSAvoidmechanical balance
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent introduces a counterbalancing mechanism that applies opposing forces to compensate for the mechanical imbalance caused by samples of different stiffness or removed sample chambers. This counterweight approach maintains the overall mechanical equilibrium of the system, allowing multiple samples to be conditioned simultaneously without compromising statistical analysis capability.

Inventive Principle:
Principle #8Anti-weight (Counterweight)

Solution Approach 2:

The system dynamically adjusts conditioning parameters such as force magnitude, displacement amplitude, or frequency for individual samples based on their stiffness characteristics. By changing these parameters adaptively, the system maintains mechanical balance while preserving the ability to perform statistical analysis across multiple samples.

Inventive Principle:
Principle #35Parameter changes

2Device complexity

If traditional support structures are used in multi-sample conditioning systems, then device complexity is reduced, but undesired alteration of the desired conditioning profile occurs and variation in conditioning profile increases

Engineering Contradiction:
Improvesupport structure simplicityVSAvoidconditioning profile consistency
Core Design Contradiction:
Device complexityVSManufacturing precision

Solution Approach 1:

The patent introduces an intermediary component between the actuator and the sample chambers that acts as a mechanical mediator. This intermediary element distributes and equalizes the conditioning forces across multiple samples, reducing variation in the conditioning profile while maintaining relatively simple device complexity.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The support structure is segmented into independent, modular units that can individually adjust to accommodate samples of different stiffness. This segmentation allows each sample chamber to receive the desired conditioning profile independently, preventing undesired alterations while keeping the overall device complexity manageable through modular design.

Inventive Principle:
Principle #1Segmentation

3Duration of action of moving object

If asymmetric loading occurs in the conditioning system, then actuator lifespan is reduced due to increased reaction loads, but maintaining perfect balance reduces adaptability to different sample configurations

Engineering Contradiction:
Improveactuator lifespanVSAvoidsample configuration flexibility
Core Design Contradiction:
Duration of action of moving objectVSAdaptability or versatility

Solution Approach 1:

The patent implements a dynamic balancing system that automatically adjusts counterbalancing forces based on the actual sample configuration and stiffness characteristics. This dynamic adaptation allows the system to maintain actuator lifespan by reducing reaction loads while simultaneously preserving adaptability to different sample configurations through real-time parameter adjustment.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution minimizes the alteration of the desired conditioning profile, reduces unwanted reaction loads on the actuator, and extends the lifespan of the actuator and support components, ensuring consistent and reliable mechanical stimulation of samples.

Implementation Method 1

a flexure allowing motion in a first direction with low friction and having high-rigidity resisting motion in at least one second direction

Methodology Applied
Scientific EffectFriction: Friction

Implementation Method 2

a flexure allowing motion in a first direction with low friction and having high-rigidity resisting motion in at least one second direction

Methodology Applied
Scientific EffectElasticity: Elasticity

Data Source

PatentEP2283338B1Multi-sample conditioning system
Publication Date: 2017.08.02 TA INSTRUMENTS WATERS LLC
  • EP2283338B1 patent drawingFigure 1
  • EP2283338B1 patent drawingFigure 2
  • EP2283338B1 patent drawingFigure 3

AI summary

A multi-sample conditioning system may include a sample chamber for each sample or a sample chamber holding one or more samples. Multiple samples enable replication for statistical analysis and individual sample chambers enable individual nutrient flow profiles for each sample. A mechanical imbalance may be created when a sample chamber is removed or when samples of different stiffness are conditioned together. The mechanical imbalance may result in an undesired alteration of the desired conditioning profile and increase the variation in the conditioning profile applied to each sample. An asymmetric-loading support assembly provides a low friction support to reduce the undesired alteration of the desired conditioning profile applied to the samples and reduce unwanted reaction loads on the conditioning drive mechanisms. The asymmetric-loading support assembly preferably includes a flexure as the low-friction, high-stiffness support. Other examples that can provide low-friction, high-stiffness support include air bearings, magnetic bearings, and hydraulic bearings.