Asymmetric Membrane Surface Porosity for Viscous Fluid Filtration

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Solution Overview

Problem

Asymmetric membranes tend to prematurely clog and have poor throughput when used with viscous or heavily loaded streams, such as food syrups, serum, and blood products, despite their high flux and throughput in water-based solutions.

Innovation Solution

Increasing the surface porosity of the tight side of asymmetric membranes by adjusting the dew point and lacquer solids concentration during the casting process or post-casting treatments like mechanical abrasion, chemical exposure, or irradiation to create a highly porous reticulated surface.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the tight side surface is made dense to achieve high flux in water-based solutions, then throughput is improved, but the membrane clogs prematurely when used with viscous or heavily loaded streams

Engineering Contradiction:
ImprovethroughputVSAvoidclogging resistance
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The membrane is designed with different surface properties at different locations: the tight side has a reticulated porous structure with larger pores to prevent clogging, while the bulk maintains the asymmetric gradient structure for high flux. This local differentiation allows the membrane to handle viscous streams without sacrificing throughput capability.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The tight side surface is transformed from a dense structure to a reticulated porous structure with interconnected larger pores. This porous configuration allows viscous and heavily loaded streams to pass through without clogging, while the underlying asymmetric structure maintains high flux performance for water-based solutions.

Inventive Principle:
Principle #31Porous materials

2Reliability

If the tight side surface is made porous to prevent clogging, then reliability is improved, but flux decreases in water-based solutions

Engineering Contradiction:
Improveclogging resistanceVSAvoidflux
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The membrane structure is segmented into distinct regions: a reticulated porous tight side surface for clogging resistance, a transition zone, and a porous bulk structure for high flux. This segmentation allows each region to optimize its function without compromising the other.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The reticulated porous structure is nested within the asymmetric membrane architecture. The larger pores of the reticulated surface are positioned upstream, containing the flux-generating asymmetric structure within them, allowing both clogging resistance and high flux to coexist.

Inventive Principle:
Principle #7Nested doll (Nesting)

3Manufacturing precision

If a dense skin is formed on the tight side to achieve high separation performance, then purification is improved, but throughput with viscous fluids deteriorates

Engineering Contradiction:
Improveseparation performanceVSAvoidthroughput
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The dense skin is replaced with a reticulated porous surface layer that has larger, interconnected pores. This porous structure maintains separation performance by providing sufficient pore density while allowing viscous fluids to pass through with reduced resistance, improving throughput.

Inventive Principle:
Principle #31Porous materials

Solution Approach 2:

The membrane combines two distinct structural features: a reticulated porous surface layer for low resistance to viscous flow and an asymmetric gradient structure for high separation performance. This composite structure integrates the benefits of both dense and porous configurations.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The modified membranes exhibit higher throughput and flux, effectively filtering viscous fluids like serum and plasma with reduced clogging, as demonstrated by improved flow times and flux rates compared to unmodified membranes.

Implementation Method 1

adjusting the dew point near the surface of a freshly cast asymmetric membrane

Methodology Applied
Scientific EffectCondensation: Condensation

Implementation Method 2

asymmetric membranes having a substantially reticulated surface microstructure by increasing the surface porosity of a tight side

Methodology Applied
Scientific EffectPhase inversion: Phase Change

Data Source

PatentEP1932581B1High-throughput asymmetric membrane and method of increasing the surface porosity of a tight side of an asymmetric membrane
Publication Date: 2012.02.22 EMD MILLIPORE CORP
  • EP1932581B1 patent drawingFigure 1A~1B
  • EP1932581B1 patent drawingFigure 2A~2B
  • EP1932581B1 patent drawingFigure 3~4

AI summary

A microporous asymmetrical membrane formed of one or more layers wherein the "tight" side of the membrane has an "opened" face or otherwise highly-porous reticulated surface is described. The microporous asymmetrical membrane has high throughput and high flux, even when used for filtering viscous materials, such as serum or plasma. The membrane's surface can be formed by ablation or solvation, or in a two or more layered structure, through an appropriate selection of casting dopes.