Atomizer With Segmented Hollow Plungers For Stable Liquid Storage

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Solution Overview

Problem

Existing atomizers are limited in their ability to store and administer formulations with different pH values, solvents, or additives, as they require stable mixing conditions, which restricts the use of combination preparations with active substances that are not stable at the same pH-value in the same solvent.

Innovation Solution

The atomizer design features two displaceable hollow plungers and separate passages within a cartridge holder, allowing two liquids to be passed through separately and combined outside the device, minimizing interactions and reactions during storage and atomization, with adjustable nozzle outlets for optimal aerosol production.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If two liquids with different pH values and solvents are stored separately in the atomizer, then the stability of the formulations is improved, but the device complexity increases due to requiring multiple separate passages and hollow plungers

Engineering Contradiction:
Improveformulation stabilityVSAvoiddevice complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The atomizer is divided into multiple independent passages (first passage, second passage) with separate hollow plungers (first hollow plunger, second hollow plunger) for each liquid formulation. This segmentation allows different formulations with incompatible pH values or solvents to be stored separately without interacting, thereby maintaining their stability while enabling combined administration when needed

Inventive Principle:
Principle #1Segmentation

2Adaptability or versatility

If multiple hollow plungers and passages are used to store separate formulations, then the adaptability for administering combination preparations is improved, but the manufacturing complexity increases

Engineering Contradiction:
Improveadaptability for combination preparationsVSAvoidease of manufacture
Core Design Contradiction:
Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

The device uses separate passages and hollow plungers for each formulation, allowing flexible loading of different liquid combinations. This modular segmented structure enables the atomizer to adapt to various combination preparation requirements while maintaining a relatively systematic manufacturing process

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The multiple passages and hollow plungers are designed with universal functionality, where each passage-plunger pair can accommodate different formulation types. This multi-functionality allows the same structural components to serve various formulation combinations, improving adaptability without proportionally increasing manufacturing complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Stability of the object's composition

If liquids are passed through separate passages and combined outside the device, then interactions and reactions during storage and atomization are minimized, but the nebulization time increases

Engineering Contradiction:
Improveminimized interactionsVSAvoidnebulization time
Core Design Contradiction:
Stability of the object's compositionVSDuration of action of moving object

Solution Approach 1:

The separate passages act as intermediary channels that allow each liquid formulation to be delivered independently to the atomization zone. By maintaining separate flow paths until the final mixing point, the system minimizes premature interactions while still enabling rapid combined nebulization through coordinated actuation of multiple hollow plungers

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This design enables the stable storage and administration of formulations with different conditions, producing aerosol clouds with controlled particle sizes for targeted lung deposition, enhancing the administration of complex medicament mixtures.

Implementation Method 1

the hollow plunger includes a valve body. Upon a downward movement of the hollow plunger, in an open position, the valve body permits an intake flow of the formulation or formulations which are already mixed, into the portion of the passage which is downstream of the hollow plunger in the flow direction. Upon an upward movement of the hollow plunger the valve body closes the hollow plunger and, upon further upward movement, the formulation or the mixture disposed downstream of the hollow plunger in the flow direction is compressed to the desired pressure.

Methodology Applied
Scientific EffectCompression: Compression

Implementation Method 2

In such an atomizer a drug solution is converted by means of high pressure of up to 500 bars into a lung-treating aerosol.

Methodology Applied
Scientific EffectNebulization: Aerosol

Implementation Method 3

Upon a downward movement of the hollow plunger, in an open position, the valve body permits an intake flow of the formulation or formulations which are already mixed, into the portion of the passage which is downstream of the hollow plunger in the flow direction. Upon an upward movement of the hollow plunger the valve body closes the hollow plunger

Methodology Applied
Scientific EffectValve mechanism: Valve

Data Source

PatentUS7819342B2Atomizer for dispensing liquids for medical purposes
Publication Date: 2010.10.26 BOEHRINGER INGELHEIM INT GMBH
  • US7819342B2 patent drawing
  • US7819342B2 patent drawing
  • US7819342B2 patent drawing

AI summary

Atomizers (1) comprising a cartridge holder (4) which is arranged in the housing (3), a mouthpiece (5) which is provided on the housing (3) and in which an atomization device (6) is arranged, and a connecting tube system (7) which connects the atomization device (6) and the cartridge holder (4), wherein the atomization device (6) has at least one nozzle body (8) and the connecting tube system (7) has at least one passage (9) with a hollow plunger (10) mounted displaceably therein, wherein the hollow plunger (10) includes a valve body (21). In accordance with a first embodiment the atomizer (1) has a first hollow plunger (10a) mounted displaceably in a first passage (9a) and a second hollow plunger (10b) mounted displaceably in a second passage (9b), wherein the first hollow plunger (10a) and the second hollow plunger (10b) extend into the cartridge holder (4).