ATP Absorption Enhancer for Nutrient Bioavailability

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Solution Overview

Problem

Existing compositions fail to effectively enhance the bioavailability of nutrients, protein, peptides, vitamins, amino acids, phytochemicals, minerals, and drugs, necessitating a solution to improve their absorption and availability.

Innovation Solution

Incorporating adenosine-5'-triphosphate (ATP) as an absorption enhancer with nutrients, protein, peptides, vitamins, amino acids, phytochemicals, minerals, and drugs to increase their bioavailability by enhancing absorption through mucosal uptake.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If ATP is combined with nutrients, protein, peptides, vitamins, amino acids, phytochemicals, minerals, fatty acids, and/or drugs, then the bioavailability and absorption of these substances are enhanced, but the complexity of the composition formulation increases

Engineering Contradiction:
ImprovebioavailabilityVSAvoidcomposition formulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines ATP with multiple nutrients, proteins, peptides, vitamins, amino acids, phytochemicals, minerals, fatty acids, and/or drugs into a single composition. This merging approach enhances the bioavailability and absorption of all components simultaneously, as ATP acts as an absorption enhancer that facilitates the uptake of these substances through mucosal tissues.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

ATP serves multiple functions within the composition: it acts as an energy source, a signaling molecule, and an absorption enhancer. By incorporating ATP, the composition achieves enhanced bioavailability for all included substances, making the formulation multi-functional and broadly applicable for improving nutrient and drug absorption.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Productivity

If ATP is administered to increase blood flow to muscle, then substrate availability and removal of metabolic waste products are improved, but the risk of adverse effects from uncontrolled ATP release increases

Engineering Contradiction:
Improvesubstrate availabilityVSAvoidadverse effects from ATP release
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent uses mucosal tissues as an intermediary mechanism for ATP delivery. ATP is administered in a controlled manner and absorbed through the mucosa, which regulates its release and prevents uncontrolled ATP accumulation in the bloodstream. This intermediary approach allows for improved substrate availability while minimizing adverse effects.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The body's natural mucosal absorption mechanisms serve to regulate and control ATP delivery to tissues. The mucosal tissues naturally absorb and distribute ATP in a controlled fashion, preventing excessive release while still achieving the desired physiological effects of improved blood flow and substrate availability.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

ATP increases the C max , T max , and AUC levels of these substances, leading to improved absorption and rapid availability at the site of action, thereby enhancing their efficacy.

Implementation Method 1

ATP acts as an absorption enhancer when administered with nutrients, protein, peptides, vitamins, amino acids, phytochemicals, minerals, fatty acids, and/or drugs. ATP increases the bioavailability of the nutrients, protein, peptides, vitamins, amino acids, phytochemicals, minerals, fatty acids, and/or drugs.

Methodology Applied
Scientific EffectMucosal uptake: Absorption (physical)

Data Source

PatentEP4025579B1Compositions containing adenosine triphosphate (ATP) and methods of use
Publication Date: 2025.07.16 TSI GRP CO LTD
  • EP4025579B1 patent drawingFigure 1~2
  • EP4025579B1 patent drawingFigure 3~5
  • EP4025579B1 patent drawingFigure 6~8

AI summary

The present invention provides a composition comprising adenosine or adenosine triphosphate (ATP) acting as an absorption enhancer when combined with a nutritional material(s) such as nutrients, protein, peptides, vitamins, phytochemicals, minerals, fatty acids, or amino acids or a drug. Methods of administering ATP or adenosine to improve the bioavailability of a nutritional material(s) such as nutrients, protein, peptides, vitamins, phytochemicals, minerals, fatty acids, or amino acids or a drug are described