Atraumatic Guidewire Distal End for Clot Circumvention
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Solution Overview
Problem
Conventional guidewires used in thrombectomy procedures often cause injury to vascular tissue and perforator vessels due to their design, which makes it difficult to navigate across clots without damaging the target vessel or entering perforator vessels.
Innovation Solution
A guidewire with an atraumatic clot-circumventing distal end, configured in shapes such as lemon, shepherd's crook, or paddle, that prevents insertion into perforator vessels while allowing safe passage over or around occlusions, featuring a widest transverse width greater than the microcatheter diameter to avoid penetration and injury, and a conformable design to complement the vessel wall.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a conventional guidewire is used to advance across a clot, then the guidewire can be advanced through the vasculature, but it causes injury to vascular tissue and may enter perforator vessels
Solution Approach 1:
The distal end of the guidewire is configured with a curved shape (such as lemon-shaped, shepherd's crook, or paddle-shaped) that allows the wire to circumvent the clot by following the curvature of the vessel wall, thereby advancing across the clot without penetrating vascular tissue or entering perforator vessels
Solution Approach 2:
The distal end of the guidewire has a different configuration than the rest of the wire body, with specific geometric shapes (lemon, shepherd's crook, paddle) designed to interact safely with the clot and vessel wall, providing localized atraumatic contact while maintaining overall wire functionality
2Adaptability or versatility
If the guidewire distal end is made flexible to navigate around the clot, then it can pass over the clot, but it may still penetrate into perforator vessels
Solution Approach 1:
The curved distal end configuration (lemon-shaped, shepherd's crook, or paddle-shaped) provides both flexibility to navigate around the clot and geometric constraints that prevent entry into perforator vessels by following the vessel wall curvature
Solution Approach 2:
The distal end has an asymmetric configuration with specific geometric shapes that are not symmetric, providing directional guidance that allows the wire to follow the vessel wall curvature and circumvent the clot while avoiding perforator vessels
3Object-affected harmful factors
If a microcatheter is advanced alone across the clot without a guidewire, then tissue injury is reduced, but it is very difficult to advance across the clot
Solution Approach 1:
The guidewire with its specially configured distal end serves as an intermediary tool that first navigates to the clot and positions itself, allowing the microcatheter to then follow over the guidewire across the clot with reduced difficulty and minimal tissue trauma
Data Source
AI summary
An endovascular medical system for use with a clot located in a target vessel. The system including a guidewire formed by a core wire. The guidewire extending in a longitudinal direction from a proximal end to an opposite atraumatic clot-circumventing configured distal end; and a lateral direction of the atraumatic clot-circumventing configured distal end of the guidewire being defined transverse to the longitudinal direction of the guidewire. The atraumatic clot-circumventing configured distal end is designed to prevent injury to an inner wall of the target vessel and prohibit insertion of any portion of the guidewire into a perforator vessel.