AuPtW Vaso-Occlusive Structure for Wide-Neck Aneurysm Retention
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Solution Overview
Problem
Existing vaso-occlusive devices face challenges in achieving a balance of columnar strength, softness, radiopacity, and MRI compatibility, particularly in treating wide-neck aneurysms, while also requiring a small delivery catheter size and minimizing procedural complexity.
Innovation Solution
The use of gold-platinum-tungsten (AuPtW) alloy in the construction of vaso-occlusive devices, specifically in the form of a mesh or coiled wire, provides enhanced columnar strength, flexibility, and radiopacity, allowing for longer devices that can be delivered through small catheters and retain position within aneurysmal sacs without additional stents.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Strength
If traditional vaso-occlusive devices are used, then the procedure is simpler, but the devices lack sufficient columnar strength for delivery through small catheters and cannot retain position in wide-neck aneurysms
Solution Approach 1:
The patent employs braided vaso-occlusive devices constructed from interwoven strands that combine structural support elements with occlusive elements. This composite structure provides enhanced columnar strength for delivery through small catheters while maintaining the ability to retain position in wide-neck aneurysms without requiring additional stents or balloons.
Solution Approach 2:
The braided structure utilizes flexible thin-wire construction that allows the device to navigate through tortuous vasculature and be delivered through small-profile catheters, while the braided configuration provides the necessary radial strength and position retention upon deployment.
2Reliability
If additional stents or balloons are deployed to retain coils in wide-neck aneurysms, then position retention is improved, but the procedure becomes more complex
Solution Approach 1:
The braided device integrates position retention functionality directly into the device structure through the interwoven braid pattern, eliminating the need for separate stents or balloons. The braid configuration provides radial strength and anchoring capability inherent to the device design.
Solution Approach 2:
The single braided device structure performs multiple functions simultaneously: it provides occlusion, maintains position in wide-neck aneurysms, and ensures reliable retention without requiring additional components or procedural steps.
3Object-affected harmful factors
If the vaso-occlusive device is made softer to prevent tissue rupture, then patient safety is improved, but the device lacks sufficient columnar strength for delivery
Solution Approach 1:
The braided construction combines soft, flexible strands in an interwoven configuration that provides overall structural strength through the braiding pattern rather than through individual strand stiffness. This allows the device to be soft and atraumatic while maintaining sufficient columnar strength for delivery through small catheters.
Solution Approach 2:
The device utilizes thin-wire braid construction that is inherently flexible and soft, preventing tissue rupture, while the braided configuration itself provides the necessary mechanical strength and rigidity for navigation and delivery through the vasculature.
Data Source
AI summary
A vaso-occlusive device, includes: a vaso-occlusive structure configured for implantation in an aneurysm sac, the vaso-occlusive structure having a delivery configuration when restrained within a delivery catheter and having a deployed configuration when released from the delivery catheter into the aneurysmal sac, at least a portion of the vaso-occlusive structure being composed of a AuPtW (gold-platinum-tungsten) alloy; wherein the AuPtW alloy comprises platinum within a range between 25% and 40% by weight, and wherein the AuPtW alloy comprises tungsten within a range between 0.01% and 10% by weight.