Reusable Auto-Injector Fluid Transfer Mechanism

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Solution Overview

Problem

Existing auto-injector devices require complex and costly manufacturing processes due to the need for pre-filled syringes, limiting reusability and increasing production costs, as they are designed for specific drugs and cannot utilize standard vials.

Innovation Solution

An auto-injector design that allows fluid transfer from a separate container, such as a standard vial, into a chamber within the device, using a biasing element to draw fluid into the chamber without external intervention, enabling the use of a single reusable sub-assembly for various drugs and promoting greater reusability of the needle assembly.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If pre-filled syringes are used in auto-injectors, then the device is ready to use immediately, but manufacturing costs increase and device reusability decreases

Engineering Contradiction:
Improvereadiness for useVSAvoidmanufacturing cost
Core Design Contradiction:
Ease of operationVSEase of manufacture

Solution Approach 1:

The device is divided into two separate components: a reusable auto-injector body and a disposable vial assembly. This segmentation allows the expensive drug-containing portion to be separate from the reusable mechanism, reducing manufacturing costs for the device maker while maintaining ease of use.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The vial is pre-filled with drug solution before being inserted into the auto-injector body. This preliminary preparation of the drug container, rather than pre-filling the entire device, allows for cost-effective manufacturing of the reusable portion while ensuring readiness for use.

Inventive Principle:
Principle #10Preliminary action

2Ease of operation

If pre-filled syringes are used in auto-injectors, then the device is ready to use immediately, but device reusability decreases

Engineering Contradiction:
Improvereadiness for useVSAvoiddevice reusability
Core Design Contradiction:
Ease of operationVSAdaptability or versatility

Solution Approach 1:

By separating the reusable auto-injector body from the disposable vial assembly, the device can be reused multiple times with different vials containing different drugs, significantly improving adaptability and versatility.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The reusable auto-injector body is designed to accommodate multiple types of vials containing different drugs, making the device universal and adaptable to various medical needs across multiple uses.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Ease of manufacture

If standard vials are used instead of pre-filled syringes, then manufacturing costs decrease, but the device complexity increases

Engineering Contradiction:
Improvemanufacturing costVSAvoidfluid transfer mechanism
Core Design Contradiction:
Ease of manufactureVSDevice complexity

Solution Approach 1:

The device employs a self-priming mechanism where the plunger automatically draws fluid from the vial into the injection chamber when the vial is inserted, eliminating the need for manual priming operations and reducing operational complexity despite the added fluid transfer components.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

A port and fluid transfer mechanism act as an intermediary between the vial and the injection chamber, automatically managing the complex fluid transfer process without requiring direct manual intervention, thus balancing manufacturing simplicity with operational ease.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Ease of operation

If manual priming operations are required, then device control is improved, but loss of time increases

Engineering Contradiction:
Improvedevice controlVSAvoidpriming time
Core Design Contradiction:
Ease of operationVSLoss of time

Solution Approach 1:

The automatic priming mechanism performs the fluid transfer operation as a preliminary action immediately when the vial is inserted, eliminating the need for separate manual priming steps and reducing the time required to prepare the device for injection.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The device automatically performs the priming operation itself through the biasing element that drives the plunger to draw fluid from the vial, eliminating the need for manual intervention and significantly reducing priming time while maintaining proper device control.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution reduces manufacturing costs by eliminating the need for pre-filled syringes, simplifies inventory management, and allows for greater reusability of the auto-injector components, while enabling the use of standard vials for drug delivery.

Implementation Method 1

An auto-injector design that allows fluid transfer from a separate container, such as a standard vial, into a chamber within the device, using a biasing element to draw fluid into the chamber without external intervention

Methodology Applied
Scientific EffectSpring mechanism: Spring

Data Source

PatentEP2326366B1Re-useable auto-injector with filling means
Publication Date: 2020.04.29 CILAG GMBH INTERNATIONAL
  • EP2326366B1 patent drawingFigure 1~2
  • EP2326366B1 patent drawingFigure 3~4
  • EP2326366B1 patent drawingFigure 5~6

AI summary

An injection device having a first sub-assembly (110) comprises a housing (111) and a chamber (112). The chamber is disposed within the housing and has proximal and distal ends, an inner surface and an exit aperture (114). The sub-assembly comprises a stopper (113) movably disposed within the chamber. The stopper has an outer surface substantially in contact with the inner surface about its perimeter. The sub-assembly comprises a port (118) adapted to receive a container (1199) containing a fluid. The stopper is fixed with respect to the housing and movement of the port causes movement of the exit aperture in relation to the stopper.