Supplementary Device for Auto-Injectors with Alignment and Monitoring

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Solution Overview

Problem

Manual injection devices pose challenges due to high injection forces, long plunger extension, and user dexterity issues, while auto-injectors may fail in monitoring medication administration schedules, leading to underdoses or needle clogging due to user forgetfulness or improper handling.

Innovation Solution

A reusable supplementary device that attaches to auto-injectors, featuring alignment features, a non-contact sensor system, and a processor for monitoring injection history, dose administration, and providing reminders, to ensure correct and timely medication delivery.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If manual injection devices are used, then the device structure is simple, but the injection force required is high and user dexterity is compromised

Engineering Contradiction:
Improvedevice structureVSAvoidinjection force
Core Design Contradiction:
Device complexityVSForce

Solution Approach 1:

The injection device is divided into two functional parts: a simple manual trigger mechanism and a separate auto-injection module containing the spring-driven plunger. The trigger releases the spring mechanism which then automatically executes the injection, separating the user interaction function from the high-force delivery function.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A spring mechanism acts as an intermediary between the user's trigger action and the plunger movement. The spring stores energy during a loading phase and releases it automatically to provide the high injection force, mediating between the low-force user input and the high-force injection requirement.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If manual injection devices are used, then the device structure is simple, but the plunger extension is long causing user inconvenience

Engineering Contradiction:
Improvedevice structureVSAvoidplunger extension
Core Design Contradiction:
Device complexityVSLength of moving object

Solution Approach 1:

The plunger mechanism is segmented into a compact retracted state and an extended injection state. The spring-loaded design allows the plunger to remain compact during handling and only extend during the automatic injection phase, reducing the effective length during user interaction.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The plunger is pre-loaded in a retracted position during device assembly and handling. The extension action is prepared in advance by compressing the spring during the loading phase, so that when triggered, the plunger extends automatically without requiring the user to manually extend a long plunger.

Inventive Principle:
Principle #10Preliminary action

3Ease of operation

If auto-injectors are used, then injection force and button extension are reduced, but monitoring of medication administration is insufficient

Engineering Contradiction:
Improveinjection operationVSAvoidmedication administration monitoring
Core Design Contradiction:
Ease of operationVSLoss of information

Solution Approach 1:

The device incorporates sensors that detect injection parameters (force, duration, completion) and provide feedback to both the user through indicators and to healthcare providers through data transmission. This closed-loop feedback system ensures proper administration and creates a monitoring record.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The auto-injector automatically monitors and records its own injection parameters without requiring external observation. The embedded sensors and processors enable the device to self-monitor injection force, duration, and completion status, and automatically transmit this information.

Inventive Principle:
Principle #25Self-service

4Ease of operation

If auto-injectors are used, then injection force and button extension are reduced, but user compliance with medication schedules is poor

Engineering Contradiction:
Improveinjection operationVSAvoidmedication schedule compliance
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The device provides real-time feedback through visual and audible indicators confirming injection completion and status. This immediate feedback helps users understand whether the injection was successful, reducing uncertainty and improving compliance with follow-up dosing schedules.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

Mechanical reminder systems are replaced with electronic monitoring and communication systems. The device uses processors, memory, and wireless communication to track administration schedules, provide digital reminders, and communicate with healthcare providers to ensure compliance.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentEP3503946B1A device for attachment to an injection device
Publication Date: 2024.12.11 SANOFI AVENTIS DEUT GMBH
  • EP3503946B1 patent drawingFigure 1A~1B
  • EP3503946B1 patent drawingFigure 2
  • EP3503946B1 patent drawingFigure 3

AI summary

A supplementary device (2) configured to be releasably attached to a drug delivery device (10). The supplementary device comprises a housing (20) having a channel (33) configured to slidably receive the drug delivery device; a first alignment feature (34) to ensure a specific alignment of the supplementary device relative to the drug delivery device and restrict rotational movement of the supplementary device around a drug delivery device; and a second alignment feature to prevent sliding movement of the supplementary device relative to the delivery device once attached thereto. The second alignment feature comprises a moveable securing member (39) biased towards the drug delivery device, and a release member (43) operable to move the securing member out of engagement with the drug delivery device.