Automated vault module

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current cryopreservation systems require manual handling of samples, which can lead to temperature fluctuations and inefficiencies in storage and retrieval processes, especially when transferring samples between cryogenic environments.

Innovation Solution

An automated cryogenic storage system with a sample handling module that maintains samples at cryogenic temperatures and allows for automated transfer between storage vaults and portable cryogenic workstations, using a robotic arm and controlled refrigeration to ensure continuous cryogenic conditions and efficient sample management.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual handling of samples is used, then device complexity is reduced, but temperature stability and reliability deteriorate due to temperature fluctuations during manual transfer

Engineering Contradiction:
Improvetemperature stabilityVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system uses automated robotic arms and refrigeration units that operate autonomously to transfer samples between storage vaults and portable workstations, eliminating the need for manual handling and maintaining temperature stability without continuous human intervention

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent introduces automated sample transfer mechanisms including robotic arms and controlled refrigeration systems as intermediaries between storage vaults and portable workstations, enabling temperature-stable transfers without direct manual handling while reducing temperature fluctuations

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If automated transfer mechanisms are implemented, then productivity and access efficiency improve, but device complexity increases

Engineering Contradiction:
Improvesample transfer efficiencyVSAvoidautomation system complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system divides the cryogenic storage facility into multiple independent storage vaults and portable workstations, each with dedicated automated transfer mechanisms, allowing parallel sample transfers and improving overall productivity while managing complexity through modular design

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The automated transfer system is designed to handle multiple sample types and transfer between different cryogenic environments (storage vaults and portable workstations) using the same robotic mechanisms, improving productivity without proportionally increasing complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If samples are kept in cryogenic environment at all times, then sample integrity is maintained, but ease of operation deteriorates due to limited access

Engineering Contradiction:
Improvesample integrityVSAvoidsample access convenience
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent introduces portable cryogenic workstations as intermediaries that can be removed from storage vaults and used outside, allowing samples to remain in cryogenic conditions during transfer while enabling convenient access and processing without compromising sample integrity

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system dynamically transitions samples between static storage in vaults and mobile processing in portable workstations, maintaining cryogenic conditions throughout the transition to preserve sample integrity while improving operational flexibility and access convenience

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables continuous cryogenic storage and retrieval of samples while maintaining temperature integrity, improving access and efficiency in handling large numbers of samples with reduced risk of temperature fluctuations during transfer.

Implementation Method 1

maintaining samples under a cryogenic temperature threshold (e.g., -134°C) at all times

Methodology Applied
Scientific EffectCryogenic cooling: Cooling

Implementation Method 2

providing an insulated and controlled cryogenic environment

Methodology Applied
Scientific EffectThermal insulation: Thermal Insulation

Data Source

PatentEP3325978B1Automated vault module
Publication Date: 2024.01.24 AZENTA US INC
  • EP3325978B1 patent drawingFigure 1A
  • EP3325978B1 patent drawingFigure 1B
  • EP3325978B1 patent drawingFigure 1C

AI summary

Cryogenic storage system provides automated storage and retrieval of samples in a cryogenic environment, as well as automated transfer of individual samples between cryogenic environments. Stored samples are maintained under a cryogenic temperature threshold, while also enabling access to the samples. The samples may be organized and tracked by scanning a barcode of each sample. Embodiments may also comprise multiple storage vaults and provide for transfer of individual samples between the storage vaults, as well as between a storage vault and a removable cryogenic storage device.