Automated Fluid Infusion Control for ECMO Systems

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Solution Overview

Problem

Existing extracorporeal circulatory support systems lack efficient mechanisms for dynamically controlling the infusion of supplements into blood based on real-time patient parameters, leading to suboptimal treatment outcomes.

Innovation Solution

The system integrates a processor, sensors, and fluid flow regulators to measure and adjust blood parameters by infusing supplemental fluids such as blood, saline, or medication, based on target values determined from patient profiles and real-time measurements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If manual monitoring and adjustment of blood parameters is used, then system complexity is reduced, but treatment precision and response time deteriorate

Engineering Contradiction:
Improveblood parameter control precisionVSAvoidsystem complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The system automatically monitors blood parameters through sensors and adjusts supplement infusion without manual intervention. The processor receives sensor signals, compares measured values to target values, and autonomously controls fluid flow regulators to maintain optimal blood parameters, enabling the system to serve itself.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system implements continuous feedback control by measuring blood parameters with sensors, comparing actual values to target values from patient profiles, and adjusting supplement infusion rates accordingly. This closed-loop feedback mechanism ensures precise control while automatically adapting to changing patient conditions.

Inventive Principle:
Principle #23Feedback

2Reliability

If continuous monitoring and adjustment is implemented, then treatment efficacy is improved, but energy consumption and operational complexity increase

Engineering Contradiction:
Improvetreatment efficacyVSAvoidenergy consumption
Core Design Contradiction:
ReliabilityVSUse of energy by moving object

Solution Approach 1:

The system maintains continuous monitoring of blood parameters and continuous adjustment of supplement infusion throughout the treatment process. Sensors continuously measure parameters, and the processor continuously regulates fluid flow to ensure blood conditions remain within optimal ranges without interruption.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The automated system performs all monitoring and adjustment functions autonomously without requiring continuous manual intervention or complex operational procedures, reducing operational complexity while maintaining treatment efficacy through self-regulation.

Inventive Principle:
Principle #25Self-service

3Speed

If automated control systems are added, then response time is improved, but device complexity and cost increase

Engineering Contradiction:
Improveresponse timeVSAvoiddevice complexity
Core Design Contradiction:
SpeedVSDevice complexity

Solution Approach 1:

The system replaces manual mechanical adjustment with automated electronic control. Sensors electronically detect blood parameters, the processor computationally determines required adjustments, and electronic fluid flow regulators automatically modify supplement infusion rates, eliminating manual mechanical operations and enabling rapid response.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The automated feedback control system rapidly detects deviations from target blood parameters and immediately adjusts supplement infusion accordingly, achieving fast response times through continuous electronic monitoring and automatic regulation without manual intervention.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS12285556B2Automated fluid infusion control for circulatory support and ECMO systems
Publication Date: 2025.04.29 ZOLL CIRCULATION INC
  • US12285556B2 patent drawing
  • US12285556B2 patent drawing
  • US12285556B2 patent drawing

AI summary

The present disclosure provides systems for controlling infusion of one or more supplements into blood received from a patient. The systems include at least one an extracorporeal circulatory support system including a pump, fluid conduits, and at least one a sensor configured to measure one or more parameters of the blood. The system also may include a fluid flow regulator coupled to the extracorporeal circulatory support system. The system receives measurement signals corresponding to parameters of blood from the at least one sensor and determines one or more target values for the parameters of blood based on a patient profile and/or the measurements. The system may control the fluid flow regulator to cause an infusion of at least one supplemental fluid from a supplemental fluid source into the blood.