Automated Sample Block Installation in Biological Analysis Systems
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Solution Overview
Problem
Existing biological analysis systems, such as PCR systems, require manual operation and intervention, leading to inefficiency and inconsistency in setup and operation, which hinders quick and effective use for diagnostics and research.
Innovation Solution
A biological analysis system with automated components, including a sample block assembly and a cover carrier, that uses RFID tags for sample and reagent identification and automated alignment and locking mechanisms to streamline the setup and operation process, allowing for automated execution of assays without user intervention.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If manual operation is used for sample block and cover installation, then system complexity is reduced, but setup time and operational consistency deteriorate
Solution Approach 1:
The sample block and cover are pre-assembled as a unified assembly before being loaded into the system. This preliminary assembly action eliminates the need for separate manual installation steps during operation, thereby increasing setup speed without requiring complex automated mechanisms for each individual component installation.
Solution Approach 2:
The sample block and cover are combined into a single integrated assembly that is handled and installed as one unit. This merging of components simplifies the installation process and reduces the number of separate operational steps, improving productivity while keeping the automation mechanism relatively simple.
2Manufacturing precision
If manual alignment is performed, then device complexity is reduced, but alignment precision and operational consistency deteriorate
Solution Approach 1:
The sample block incorporates asymmetric features such as a protrusion that fits into a corresponding recess in the cover. This asymmetric design provides inherent alignment guidance, ensuring precise positioning without requiring complex automated alignment mechanisms, as the asymmetric geometry naturally guides the components into the correct relative position.
Solution Approach 2:
The alignment features on the sample block and cover enable self-alignment during the installation process. The protrusion and recess geometry automatically guide the components into proper alignment as they are assembled, eliminating the need for external alignment mechanisms and maintaining high precision without added complexity.
3Reliability
If automated installation is implemented, then operational consistency is improved, but ease of operation deteriorates
Solution Approach 1:
By pre-assembling the sample block and cover together before loading into the system, the automation mechanism only needs to handle the unified assembly rather than coordinating multiple separate components. This preliminary action simplifies the automated installation process, maintaining operational consistency while reducing the complexity of user interaction requirements.
Data Source
AI summary
A biological analysis system for performing a performing an assay or experiment includes one or more of a carrier, base, or tray. The carrier, base, or tray is/are configured to interchangeably receive (1) a first block and a corresponding first cover placed over the first block or (2) a second block and a corresponding second cover placed over the second block; The system also includes a computer readable memory comprising instructions for detecting when the second cover is placed over the first block and/or for detecting when the first cover is placed over the second block based on lack of electrical continuity along an electrical path comprising one of the blocks and one of the covers.