Automated Titration in Medical Infusion Devices
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Solution Overview
Problem
Titrating the initial dosage of medicaments delivered by medical infusion devices is often time-consuming and requires frequent patient visits to healthcare providers, as existing systems lack efficient mechanisms to account for patient side effects during dose escalation.
Innovation Solution
Incorporating titration schemes into medical infusion devices that allow automatic escalation of dosing based on patient side effect inputs, using a pump mechanism and control electronics to increase the medication delivery rate if no side effects are reported, up to a maximum predetermined rate, and seamlessly transitioning between devices to maintain consistent treatment.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If manual titration by healthcare providers is used, then patient safety and side effect monitoring are improved, but the number of patient visits and time required for dose escalation increase
Solution Approach 1:
The infusion device automatically performs dose escalation titration by monitoring patient side effects and adjusting delivery rates without requiring healthcare provider intervention at each step. The device serves itself by making intelligent dosing decisions based on patient feedback, reducing the need for frequent patient visits while maintaining safety through automated monitoring and adjustment protocols.
2Measurement precision
If frequent patient visits to healthcare providers are required, then accurate monitoring of side effects is improved, but patient convenience and treatment efficiency deteriorate
Solution Approach 1:
The system implements continuous feedback loops where patient side effect reports are immediately processed by the control electronics, which automatically adjust the pump delivery rate in response. This real-time feedback mechanism enables accurate side effect monitoring to occur remotely without requiring frequent in-person patient visits, as the device continuously adapts dosing based on patient responses.
3Loss of time
If automated titration is implemented, then the number of patient visits and time required for dose escalation are reduced, but device complexity increases
Solution Approach 1:
The control electronics are designed to perform multiple functions: monitoring side effects, determining titration schemes, controlling pump delivery rates, and managing device operation. By making the control system universal and multi-functional, the patent reduces overall device complexity while enabling automated titration, as a single intelligent control unit handles all aspects of dose escalation rather than requiring separate specialized components.
4Device complexity
If manual dose control is used, then device simplicity is maintained, but productivity and treatment efficiency decrease
Solution Approach 1:
The device incorporates pre-programmed titration schemes and algorithms that automatically guide dose escalation. By preparing and storing multiple titration protocols in advance, the system can quickly select and execute appropriate dosing strategies without requiring complex real-time calculations or manual intervention, thus improving treatment efficiency while maintaining relatively simple device architecture.
Data Source
AI summary
Titration schemes are carried out by medical infusion devices, such as ambulatory or implantable infusion devices. The titration schemes carried out by infusion systems and devices may take into account patient side effects in controlling the rate at which a medicament is delivered from the devices of systems.


