Automated Vessel Pathology Detection and FFR Analysis

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Solution Overview

Problem

Current clinical practices for analyzing artery diseases rely on visual assessment and require heavy user input, leading to slow processing times and the inability to provide immediate, real-time results.

Innovation Solution

A fully automated system for vessel analysis from image data that detects pathologies without user input, tracks them across multiple images, and provides real-time analysis of functional measurements like FFR, using computer vision techniques and virtual marks.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If visual assessment and manual marking are used for vessel analysis, then measurement precision can be achieved, but processing time increases and real-time results cannot be provided

Engineering Contradiction:
Improvemeasurement precisionVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs automated detection of vessel pathologies and functional measurements without requiring manual user input or marking. The computer vision system independently identifies stenoses and calculates FFR values, eliminating the need for health professional intervention in the measurement process itself.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces manual mechanical marking and visual assessment with automated computer vision algorithms. The system uses image processing techniques to automatically detect pathologies and calculate functional measurements, substituting human expertise with computational methods.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If 3D model reconstruction is used for functional measurements, then measurement precision improves, but device complexity and memory requirements increase

Engineering Contradiction:
Improvefunctional measurement accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system extracts functional measurement calculations directly from 2D angiogram images without requiring full 3D model reconstruction. By extracting necessary geometric and functional parameters from the 2D images themselves, the system avoids the complexity of 3D modeling while maintaining measurement accuracy.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

Instead of reconstructing complete 3D models, the system performs partial analysis using 2D image data to calculate functional measurements. This partial action approach provides sufficient measurement precision without the excessive complexity of full 3D reconstruction.

Inventive Principle:
Principle #16Partial or excessive action

3Adaptability or versatility

If manual marking and user input are required, then adaptability to different cases improves, but ease of operation decreases and real-time processing is prevented

Engineering Contradiction:
Improvecase-specific adaptabilityVSAvoiduser interaction requirement
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The system automatically adapts to different vessel cases by using computer vision algorithms that can identify pathologies and calculate functional measurements independently. The system self-adjusts to different imaging conditions and vessel geometries without requiring user guidance or input.

Inventive Principle:
Principle #25Self-service

4Productivity

If automated detection without tracking is used, then processing speed increases, but measurement precision decreases due to inability to identify same pathology across images

Engineering Contradiction:
Improveprocessing speedVSAvoidpathology identification accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system uses virtual marks as feedback mechanisms to track and identify the same pathology across multiple images. The virtual marks provide reference points that enable the system to consistently locate and measure the same stenosis in different angiogram frames, maintaining precision while processing images automatically.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS20250117941A1Automated analysis of image data to determine fractional flow reserve
Publication Date: 2025.04.10 MEDHUB LTD
  • US20250117941A1 patent drawing
  • US20250117941A1 patent drawing
  • US20250117941A1 patent drawing

AI summary

A system and method for analysis of a vessel automatically detects a pathology in a first image of the vessel and attaches a virtual mark to the pathology in the first image. The system may detect the same pathology in a second image of the vessel, based on the virtual mark, and may then provide analysis (e.g., determine an FFR value) of the pathology based on the pathology detected in the first and second images.