Automatic Base Dose Generation for Radiation Therapy

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Solution Overview

Problem

Current radiation therapy treatment plans are prone to human error due to manual calculation of the base dose, leading to inaccurate dosing and sub-optimal treatment plans, as they fail to efficiently account for both delivered and undelivered radiation dosages from various sources.

Innovation Solution

An automatic control circuit generates a base dose by referencing dosing information from multiple sources, including previous and future treatments, patient images, and deformation information, allowing for weighting and uncertainty indication to optimize radiation therapy plans and limit radiation accumulation in target and untargeted volumes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual calculation of base dose is used, then human judgment and flexibility are applied, but human error and inaccuracy increase

Engineering Contradiction:
Improvebase dose calculation accuracyVSAvoidtreatment plan reliability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent replaces the manual mechanical calculation process with an automated computer-based system. The control circuit automatically retrieves dosing information from multiple sources, applies deformation information, and calculates the base dose without human intervention, thereby eliminating human error while maintaining calculation accuracy.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system performs self-service by automatically gathering dosing information from multiple sources, processing deformation data, and generating the base dose calculation independently without requiring manual human input or judgment, improving both accuracy and reliability.

Inventive Principle:
Principle #25Self-service

2Loss of information

If multiple sources of dosing information are integrated, then comprehensive dosing accounting is achieved, but system complexity increases

Engineering Contradiction:
Improvedosing information completenessVSAvoidinformation integration complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The control circuit is designed with multi-functionality to handle various types of dosing information from different sources (previous treatments, future treatments, imaging procedures) and process them through a unified algorithm that incorporates deformation information, achieving comprehensive information integration without proportionally increasing system complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent introduces deformation information as an intermediary element that mediates between raw dosing information from multiple sources and the final base dose calculation. This intermediary allows the system to harmonize data from different sources and time points by accounting for anatomical changes, simplifying the integration process.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Measurement precision

If deformation information is incorporated, then anatomical accuracy is improved, but calculation complexity increases

Engineering Contradiction:
Improveanatomical dosing accuracyVSAvoidcalculation process complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system performs preliminary action by retrieving and storing deformation information in advance before the base dose calculation is performed. This pre-prepared deformation data is then automatically applied during the calculation process, improving anatomical accuracy without adding complexity to the actual calculation step.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS11191978B2Apparatus and method using automatic generation of a base dose
Publication Date: 2021.12.07 SIEMENS HEALTHINEERS INTERNATIONAL AG
  • US11191978B2 patent drawing

AI summary

A control circuit forms a radiation therapy treatment plan by automatically generating a base dose that references dosing information from multiple sources and then using that base dose to optimize a radiation therapy treatment plan. That radiation therapy treatment plan is then used to administer radiation therapy to a patient. That automatically generated base dose can represent any or all of earlier radiation therapy treatments for the patient, a same fraction as a dose presently being optimized per the radiation therapy treatment plan, and future planned fractions for the patient.